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A novel long chain polyunsaturated fatty acid, β-oxa 21:3 n -3, inhibits T lymphocyte proliferation, cytokine production, delayed-type hypersensitivity, and carrageenan-induced paw reaction and selectively targets intracellular signals

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Date

2001

Authors

Costabile, Maurizio
Hii, Charles
Robinson, Brenton S
Rathjen, Deborah A
Pitt, Michael
Easton, Christopher
Miller, Robert C
Poulos, Alf
Murray, Andrew
Ferrante, Antonio

Journal Title

Journal ISSN

Volume Title

Publisher

American Association of Immunologists

Abstract

A novel polyunsaturated fatty acid (PUFA) β-oxa 21:3n-3, containing an oxygen atom in the β position, was chemically synthesized, and found to have more selective biological activity than the n-3 PUFA, docosahexaenoic acid (22:6n-3) on cells of the immu

Description

Keywords

Keywords: docosahexaenoic acid; polyunsaturated fatty acid; antiinflammatory activity; article; delayed hypersensitivity; human; human cell; lymphocyte proliferation; paw edema; priority journal; signal transduction; T lymphocyte; Anti-Inflammatory Agents; Carragee

Citation

URI

http://hdl.handle.net/1885/92595

Collections

ANU Research Publications

Source

Journal of Immunology

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

Restricted until

2037-12-31

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