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Item type: Publication , Access status: Metadata only , A Hundred Years of Han (vol.2): Being the Chronicle of the Later Han Dynasty for the Years 57 to 156 AD as Recorded in Chapters 44 to 53 of the Zizhi tongjian of Sima Guang(Brill, 2025) De Crespigny, RafeThis is Volume 2 of a 2-volume set: Compiled by the scholar statesman Sima Guang of the Song dynasty, Zizhi tongjian is well recognised as one of the major histories of China. In length and extent, Later or Eastern Han was one of the great empires of east Asia, and its eventual failure led to the heroic age of the Three Kingdoms and centuries of division between north and south. Sima Guang's account of the dynasty's successes and failures provides detailed and informed information on the nature and governance of the Chinese imperial state. This translation offers a Western reader access to and an understanding of that world.Item type: Publication , Access status: Metadata only , Investment in an accessible multimodal active network: How project life cycle and investment horizon can impact the design(2025) Memarpour, Mehrdad; Najmi, Ali; Waller, S. Travis; Hossein Rashidi, TahaThe negative social and environmental impacts of car-oriented road designs have led transport policymakers to concentrate on alternative modes of travel in their recent development plans. However, in this paradigm shift, they must deal with the challenge of allocating limited resources to non-car users of transport networks in the most efficient manner. In this study, we address the resource allocation problem to maximise the accessibility of active modes on a multimodal network, accounting for the comfort of car and bus users, from a cost-benefit analysis (CBA) perspective. A bilevel optimisation model is developed in which, at the upper level, a planner moderates the network configuration by making investments in bus frequency and bike lane development to maximise the accessibility of the cycling mode over a pre-determined investment horizon and project life cycle considering a budget constraint containing operating and long-term funds. A combined modal split and traffic assignment (CMSTA) problem is considered at the lower level. The bilevel problem is converted to a single-level non-linear optimisation model by implementing KKT conditions. In a nutshell, our analysis shows that when the project life cycle is less than the planner's investment horizon, having the option to modify the design throughout the horizon (dynamic designs) leads to higher average accessibility levels compared to static designs where that option does not exist. Furthermore, charging users to use the network regardless of the link type they choose provides cyclists with higher accessibility levels. Finally, difference in value of time among users can negatively impact accessibility of cyclists.Item type: Publication , Access status: Metadata only , Planning laws and Aboriginal and Torres Strait Islander peoples’ rights and interests(2023) Wensing, EdContemporary Australian planning has for too long ignored its fundamental responsibilities in its relations with Aboriginal and Torres Strait Islander peoples in urban and regional Australia. Australian land-use planning and development processes do not have a good track record of taking account of the rights and interests of Aboriginal and Torres Strait Islander peoples, or of adequately involving them, especially in our capital cities and major regional centres where the larger proportion of Aboriginal and Torres Strait Islander peoples live and the where the extent of dispossession is perhaps at its greatest. It is a sad indictment of our planning system that more than 30 years after the High Court of Australia’s landmark decision in Mabo (No. 2), that most of the planning statutes around Australia still do not require prior consultation with or the direct involvement of registered native title holders or claimants during plan formulation or decision-making about land uses for an area of land or waters. This paper examines the current state of affairs with respect to how well or otherwise our planning statutes still fail to give adequate recognition to Aboriginal and Torres Strait Islander peoples’ rights and interests in contemporary statutory planning processes.Item type: Publication , Access status: Metadata only , Glycerol and Glycerol-3-Phosphate: Multifaceted Metabolites in Metabolism, Cancer, and Other Diseases(2025) Madiraju, S. R.Murthy; Possik, Elite; Al-Mulla, Fahd; Nolan, Christopher J.; Prentki, MarcGlycerol and glycerol-3-phosphate (Gro3P) are key metabolites at the intersection of carbohydrate, lipid, and energy metabolism. Their production and usage are organismal and cell-type specific. Glycerol has unique physicochemical properties enabling it to function as an osmolyte, protein structure stabilizer, and an antimicrobial and antifreeze agent, important to the preservation of many biological functions. Glycerol and Gro3P are implicated in many physiological and disease processes relating to energy metabolism, thermoregulation, hydration, skin health, male fertility, aging, and cancer. Glycerol has countless applications in the food, pharmaceutical, and cosmetics industries. It is used as a sweetener, preservative, thickening agent, humectant, osmolyte, and cryoprotectant. It is widely used in skin and wound care products, laxatives, in cell and tissue preservation, and in medicines for numerous conditions. Here, we review the multiple uses and functions of glycerol and Gro3P and associated transporters, enzymes, and target genes in health, senescence, and disease. We discuss the evidence that glycerol may be present at much higher levels in tissues and cells than in the blood. We bring particular focus to the newly identified glycerol shunt in the direct formation of glycerol independent of lipolysis and as a pathway allowing cells to adapt to various stresses. Relevant to chronic metabolic diseases, cancer and aging, glycerol and Gro3P present important translational implications and thus warrant much more attention.Item type: Publication , Access status: Metadata only , Continual Learning and Unknown Object Discovery in 3D Scenes via Self-distillation(Springer Science+Business Media B.V., 2025) Boudjoghra, Mohamed El Amine; Lahoud, Jean; Cholakkal, Hisham; Anwer, Rao Muhammad; Khan, Salman; Khan, Fahad ShahbazOpen-world 3D instance segmentation is a recently introduced problem with diverse applications, notably in continually learning embodied agents. This task involves segmenting unknown instances and learning new instances when their labels are introduced. However, prior research in the open-world domain has traditionally addressed the two sub-problems, namely continual learning and unknown object identification, separately. This approach has resulted in limited performance on unknown instances and cannot effectively mitigate catastrophic forgetting. Additionally, these methods bypass the utilization of the information stored in the previous version of the continual learning model, instead relying on a dedicated memory to store historical data samples, which inevitably leads to an expansion of the memory budget. In this paper, we argue that continual learning and unknown object identification are desired to be tackled in conjunction. To this end, we propose a new exemplar-free approach for 3D continual learning and unknown object discovery through continual self-distillation. Our approach, named OpenDistill3D, leverages the pseudo-labels generated by the model from the preceding task to improve the unknown predictions during training while simultaneously mitigating catastrophic forgetting. By integrating these pseudo-labels into the continual learning process, we achieve enhanced performance in handling unknown objects. We validate the efficacy of the proposed approach via comprehensive experiments on various splits of the ScanNet200 dataset, showcasing superior performance in contin vual learning and unknown object retrieval compared to the state-of-the-art. Code and model are available at github.com/aminebdj/OpenDistill3D.