A novel long chain polyunsaturated fatty acid, β-oxa 21:3 n -3, inhibits T lymphocyte proliferation, cytokine production, delayed-type hypersensitivity, and carrageenan-induced paw reaction and selectively targets intracellular signals

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dc.contributor.authorCostabile, Maurizio
dc.contributor.authorHii, Charles
dc.contributor.authorRobinson, Brenton S
dc.contributor.authorRathjen, Deborah A
dc.contributor.authorPitt, Michael
dc.contributor.authorEaston, Christopher
dc.contributor.authorMiller, Robert C
dc.contributor.authorPoulos, Alf
dc.contributor.authorMurray, Andrew
dc.contributor.authorFerrante, Antonio
dc.date.accessioned2015-12-13T23:25:50Z
dc.date.issued2001
dc.date.updated2015-12-12T09:44:17Z
dc.description.abstractA novel polyunsaturated fatty acid (PUFA) β-oxa 21:3n-3, containing an oxygen atom in the β position, was chemically synthesized, and found to have more selective biological activity than the n-3 PUFA, docosahexaenoic acid (22:6n-3) on cells of the immu
dc.identifier.issn0022-1767
dc.identifier.urihttp://hdl.handle.net/1885/92595
dc.publisherAmerican Association of Immunologists
dc.sourceJournal of Immunology
dc.subjectKeywords: docosahexaenoic acid; polyunsaturated fatty acid; antiinflammatory activity; article; delayed hypersensitivity; human; human cell; lymphocyte proliferation; paw edema; priority journal; signal transduction; T lymphocyte; Anti-Inflammatory Agents; Carragee
dc.titleA novel long chain polyunsaturated fatty acid, β-oxa 21:3 n -3, inhibits T lymphocyte proliferation, cytokine production, delayed-type hypersensitivity, and carrageenan-induced paw reaction and selectively targets intracellular signals
dc.typeJournal article
local.bibliographicCitation.issue7
local.bibliographicCitation.lastpage3987
local.bibliographicCitation.startpage3980
local.contributor.affiliationCostabile, Maurizio, University of Adelaide
local.contributor.affiliationHii, Charles, Women's and Children's Hospital
local.contributor.affiliationRobinson, Brenton S, Women's and Children's Hospital
local.contributor.affiliationRathjen, Deborah A, Boinomics Ltd
local.contributor.affiliationPitt, Michael, College of Physical and Mathematical Sciences, ANU
local.contributor.affiliationEaston, Christopher, College of Physical and Mathematical Sciences, ANU
local.contributor.affiliationMiller, Robert C, Peptech Ltd.
local.contributor.affiliationPoulos, Alf, Women's and Children's Hospital
local.contributor.affiliationMurray, Andrew, Flinders University
local.contributor.affiliationFerrante, Antonio, Women's and Children's Hospital
local.contributor.authoruidPitt, Michael, u3395237
local.contributor.authoruidEaston, Christopher, u9500570
local.description.embargo2037-12-31
local.description.notesImported from ARIES
local.description.refereedYes
local.identifier.absfor030499 - Medicinal and Biomolecular Chemistry not elsewhere classified
local.identifier.ariespublicationMigratedxPub25726
local.identifier.citationvolume167
local.identifier.scopusID2-s2.0-0035478351
local.type.statusPublished Version

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