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Hypertolerance to morphine in G(zalpha)-deficient mice

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dc.contributor.authorHendry, Ian
dc.contributor.authorKelleher, Kim
dc.contributor.authorBartlett, Selena
dc.contributor.authorLeck, Kwong-Joo
dc.contributor.authorReynolds, Anna
dc.contributor.authorHeydon, Katharina
dc.contributor.authorMellick, A
dc.contributor.authorMegirian, David
dc.contributor.authorMatthaei, Klaus
dc.date.accessioned2015-12-13T23:15:43Z
dc.date.issued2000
dc.date.updated2015-12-12T08:44:51Z
dc.description.abstractOur laboratory has generated a mouse deficient in the alpha (α) subunit of the G protein, G(z), (G(zα)) gene and we have examined the involvement of G(zα) in spinal and supraspinal analgesia and tolerance mechanisms. Spinal analgesia was tested by the
dc.identifier.issn0006-8993
dc.identifier.urihttp://hdl.handle.net/1885/89026
dc.publisherElsevier
dc.sourceBrain Research
dc.subjectKeywords: delta opiate receptor; guanine nucleotide binding protein; morphine; mu opiate receptor; protein subunit; analgesia; animal experiment; animal tissue; article; controlled study; hot plate test; morphine tolerance; mouse; nonhuman; priority journal; reacti Analgesia; Behavioral testing; G protein; G(za)-deficient mice; G(z); Morphine tolerance; Opioid receptor
dc.titleHypertolerance to morphine in G(zalpha)-deficient mice
dc.typeJournal article
local.bibliographicCitation.lastpage19
local.bibliographicCitation.startpage10
local.contributor.affiliationHendry, Ian, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationKelleher, Kim, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationBartlett, Selena, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationLeck, Kwong-Joo, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationReynolds, Anna, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationHeydon, Katharina, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationMellick, A, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationMegirian, David, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationMatthaei, Klaus, College of Medicine, Biology and Environment, ANU
local.contributor.authoruidHendry, Ian, u7600265
local.contributor.authoruidKelleher, Kim, u9613593
local.contributor.authoruidBartlett, Selena, u9505280
local.contributor.authoruidLeck, Kwong-Joo, u9200205
local.contributor.authoruidReynolds, Anna, u3050743
local.contributor.authoruidHeydon, Katharina, t406
local.contributor.authoruidMellick, A, u3847112
local.contributor.authoruidMegirian, David, u4120945
local.contributor.authoruidMatthaei, Klaus, u8200697
local.description.embargo2037-12-31
local.description.notesImported from ARIES
local.description.refereedYes
local.identifier.absfor060104 - Cell Metabolism
local.identifier.ariespublicationMigratedxPub18926
local.identifier.citationvolume870
local.identifier.doi10.1016/S0006-8993(00)02387-8
local.identifier.scopusID2-s2.0-0034617376
local.type.statusPublished Version

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