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An asymmetric synthesis of ADDA and ADDA-glycine dipeptide using the b-lactam synthon method

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dc.contributor.authorCundy, Darren
dc.contributor.authorDonohue, Anthony
dc.contributor.authorMcCarthy, Thomas D
dc.date.accessioned2015-12-13T23:35:08Z
dc.date.available2015-12-13T23:35:08Z
dc.date.issued1999
dc.date.updated2015-12-12T09:38:49Z
dc.description.abstractThe paper describes the synthesis of the W-Boc lactam 4, and demonstrates that it is an important intermediate in the synthesis of dipeptide 5 (X = H, n = 0, R = Me), an analogue of the ADDA-GIu dipeptide 3. In addition we have described a mild method for the preparation of the amino acid salt ADDA-HC1, and provided synthetic methods, and full characterisation for the previously 'elusive' free amino acid ADDA.
dc.identifier.issn0300-922X
dc.identifier.urihttp://hdl.handle.net/1885/93773
dc.publisherRoyal Society of Chemistry
dc.sourceRoyal Chemical Society Journal Perkin Transactions
dc.titleAn asymmetric synthesis of ADDA and ADDA-glycine dipeptide using the b-lactam synthon method
dc.typeJournal article
local.bibliographicCitation.startpage559?567
local.contributor.affiliationCundy, Darren, CSIRO
local.contributor.affiliationDonohue, Anthony, CSIRO
local.contributor.affiliationMcCarthy, Thomas D, College of Physical and Mathematical Sciences, ANU
local.contributor.authoruidMcCarthy, Thomas D, u970750
local.description.notesImported from ARIES
local.description.refereedYes
local.identifier.absfor030503 - Organic Chemical Synthesis
local.identifier.ariespublicationMigratedxPub25179
local.identifier.scopusID2-s2.0-0003003684
local.type.statusPublished Version

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