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The Role of Endoplasmic Reticulum Stress in Nonimmune Diabetes: NOD.k iHEL, a Novel Model of β Cell Death

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dc.contributor.authorSocha, L
dc.contributor.authorSilva, Diego
dc.contributor.authorLesage, Sylvie
dc.contributor.authorGoodnow, Christopher
dc.contributor.authorPetrovsky, Nikolai
dc.date.accessioned2015-12-13T23:07:20Z
dc.date.issued2003
dc.date.updated2015-12-12T08:08:48Z
dc.description.abstractThe final common pathway in diabetes development is β cell apoptosis. We herein describe a novel diabetes model based on transgenic NOD.k iHEL mice, wherein male mice develop diabetes due to nonimmune-mediated β cell death. Histology and electron micros
dc.identifier.issn0077-8923
dc.identifier.urihttp://hdl.handle.net/1885/86166
dc.publisherNew York Academy of Sciences
dc.sourceAnnals of the New York Academy of Sciences
dc.subjectKeywords: animal cell; animal experiment; animal model; animal tissue; cell death; cell function; conference paper; controlled study; endoplasmic reticulum; glucose tolerance test; histopathology; male; mouse; non insulin dependent diabetes mellitus; nonhuman; panc ß cell; Cell death; Diabetes; Endoplasmic reticulum (ER) stress; NOD.k iHEL
dc.titleThe Role of Endoplasmic Reticulum Stress in Nonimmune Diabetes: NOD.k iHEL, a Novel Model of β Cell Death
dc.typeJournal article
local.bibliographicCitation.lastpage183
local.bibliographicCitation.startpage178
local.contributor.affiliationSocha, L, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationSilva, Diego, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationLesage, Sylvie, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationGoodnow, Christopher, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationPetrovsky, Nikolai, College of Medicine, Biology and Environment, ANU
local.contributor.authoruidSocha, L, u3266083
local.contributor.authoruidSilva, Diego, u3266309
local.contributor.authoruidLesage, Sylvie, u9913892
local.contributor.authoruidGoodnow, Christopher, u9710462
local.contributor.authoruidPetrovsky, Nikolai, a160237
local.description.embargo2037-12-31
local.description.notesImported from ARIES
local.description.refereedYes
local.identifier.absfor100109 - Transgenesis
local.identifier.ariespublicationMigratedxPub14947
local.identifier.citationvolume1005
local.identifier.doi10.1196/annals.1288.022
local.identifier.scopusID2-s2.0-1942475176
local.type.statusPublished Version

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