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Assignment of the 13 C and 15 N NMR spectra of the antitumour antibiotic streptonigrin

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dc.contributor.authorHarding, Margaret
dc.contributor.authorAnderberg, Pia I
dc.contributor.authorLuck, Ian J
dc.date.accessioned2015-12-13T22:26:27Z
dc.date.issued2002
dc.date.updated2015-12-11T08:22:21Z
dc.description.abstractThe assignments of the two pyridyl nitrogens and two amino nitrogens in the antitumour antibiotic streptonigrin, and all carbon resonances, were determined by 15N (HSQC, HMBC) and 13C (HSQC, HMBC) NMR techniques. These data provide useful probes for determination of the site(s) of metal complexation in the drug, which are important in the mechanism of antitumour activity.
dc.identifier.issn0749-1581
dc.identifier.urihttp://hdl.handle.net/1885/73519
dc.publisherJohn Wiley & Sons Inc
dc.sourceMagnetic Resonance in Chemistry
dc.subjectKeywords: antibiotic agent; antineoplastic agent; metal complex; nitrogen derivative; rufocromomycin; antineoplastic activity; article; carbon nuclear magnetic resonance; complex formation; drug structure; nuclear magnetic resonance spectroscopy; structure activity 2,2'-bipyridyl; 13C NMR; 15N NMR; Aminoquinone; Metal complex; NMR; Streptonigrin
dc.titleAssignment of the 13 C and 15 N NMR spectra of the antitumour antibiotic streptonigrin
dc.typeJournal article
local.bibliographicCitation.issue4
local.bibliographicCitation.lastpage315
local.bibliographicCitation.startpage313
local.contributor.affiliationHarding, Margaret, Administrative Division, ANU
local.contributor.affiliationAnderberg, Pia I, University of Sydney
local.contributor.affiliationLuck, Ian J, University of Sydney
local.contributor.authoruidHarding, Margaret, u4044881
local.description.embargo2037-12-31
local.description.notesImported from ARIES
local.identifier.absfor030600 - PHYSICAL CHEMISTRY (INCL. STRUCTURAL)
local.identifier.ariespublicationf5625xPUB3724
local.identifier.citationvolume40
local.identifier.doi10.1002/mrc.997
local.identifier.scopusID2-s2.0-0142024151
local.type.statusPublished Version

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