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Targeting of C-Type lectin-like receptor 2 or P2Y12 for the preention of platelet

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dc.contributor.authorFlierl, Ulrike
dc.contributor.authorNero, T.L
dc.contributor.authorLim, B
dc.contributor.authorAndrews, Robert K
dc.contributor.authorParker, Michael William
dc.contributor.authorGardiner, Elizabeth
dc.contributor.authorPeter, Karlheinz
dc.date.accessioned2021-12-08T23:54:43Z
dc.date.issued2018
dc.date.updated2023-10-29T07:15:43Z
dc.description.abstractEssentials CpG oligodeoxynucleotide (ODN) immuotherapeutics cause undesired platelet activating effects. It is crucial to understand the mechanisms of these effects to identify protective strategies. CpG ODN-induced platelet activation depends on C-type lectin-like receptor 2 (CLEC-2) and P2Y12. Targeting CLEC-2 or P2Y12 fully prevents CpG ODN-induced platelet activation and thrombosis.
dc.format.mimetypeapplication/pdfen_AU
dc.identifier.issn1538-7933en_AU
dc.identifier.urihttp://hdl.handle.net/1885/255030
dc.language.isoen_AUen_AU
dc.publisherWiley
dc.rights© 2017 International Society on Thrombosis and Haemostasis
dc.sourceJournal of Thrombosis and Haemostasis
dc.titleTargeting of C-Type lectin-like receptor 2 or P2Y12 for the preention of platelet
dc.typeJournal article
local.bibliographicCitation.issue1en_AU
local.bibliographicCitation.lastpage185en_AU
local.bibliographicCitation.startpage181en_AU
local.contributor.affiliationFlierl, Ulrike, University of Melbourneen_AU
local.contributor.affiliationNero, T.L, St Vincent's Institute of Medical Researchen_AU
local.contributor.affiliationLim, B, Baker Heart & Diabetes Instituteen_AU
local.contributor.affiliationAndrews, Robert K, Monash Universityen_AU
local.contributor.affiliationParker, Michael William, St Vincent's Institute, Biota Str Biol Laben_AU
local.contributor.affiliationGardiner, Elizabeth, College of Health and Medicine, ANUen_AU
local.contributor.affiliationPeter, Karlheinz, Baker IDI Heart & Diabetes Instituteen_AU
local.contributor.authoruidGardiner, Elizabeth, u1023050en_AU
local.description.embargo2099-12-31
local.description.notesImported from ARIESen_AU
local.identifier.absfor060110 - Receptors and Membrane Biologyen_AU
local.identifier.absseo970106 - Expanding Knowledge in the Biological Sciencesen_AU
local.identifier.ariespublicationu1000203xPUB1en_AU
local.identifier.citationvolume16en_AU
local.identifier.doi10.1111/jth.13877en_AU
local.identifier.scopusID2-s2.0-85040027838
local.identifier.thomsonIDWOS:000419402000024
local.publisher.urlhttps://www.wiley.com/en-gben_AU
local.type.statusPublished Versionen_AU

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