New insights into the protective power of platelets in malaria infection

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dc.contributor.authorMcMorran, Brendan
dc.contributor.authorBurgio, Gaetan
dc.contributor.authorFoote, Simon
dc.date.accessioned2018-11-29T22:56:24Z
dc.date.available2018-11-29T22:56:24Z
dc.date.issued2013
dc.date.updated2018-11-29T08:12:02Z
dc.description.abstractPlatelets, as well as regulating blood hemostasis, are an important component of thebody's defense against invading microbial pathogens. We previously reported that platelets protect during malaria infection by binding Plasmodiuminfected erythrocytes (IE) and killing the parasite within. More recent studies have now revealed the platelet plasmocidalfactor, platelet factor 4 (PF4) and the red cell-expressed Duffyantigen molecule as the central players in the parasite killing activity of platelets.
dc.format.mimetypeapplication/pdfen_AU
dc.identifier.issn1942-0889
dc.identifier.urihttp://hdl.handle.net/1885/153509
dc.publisherLandes Bioscience
dc.sourceCommunicative & Integrative Biology
dc.subjectKeywords: Plasmodium falciparum Duffy-antigen; Innate immunity; Malaria; Plasmodium falciparum; Platelet; Platelet factor 4
dc.titleNew insights into the protective power of platelets in malaria infection
dc.typeJournal article
dcterms.accessRightsOpen Accessen_AU
local.bibliographicCitation.issue3
local.bibliographicCitation.lastpagee23653
local.bibliographicCitation.startpagee23653
local.contributor.affiliationMcMorran, Brendan, College of Health and Medicine, ANU
local.contributor.affiliationBurgio, Gaetan, College of Health and Medicine, ANU
local.contributor.affiliationFoote, Simon, College of Health and Medicine, ANU
local.contributor.authoremailu5267721@anu.edu.au
local.contributor.authoruidMcMorran, Brendan, u5267721
local.contributor.authoruidBurgio, Gaetan, u5727247
local.contributor.authoruidFoote, Simon, u5697711
local.description.notesImported from ARIES
local.identifier.absfor060499 - Genetics not elsewhere classified
local.identifier.absfor110803 - Medical Parasitology
local.identifier.absfor111203 - Cancer Genetics
local.identifier.ariespublicationa383154xPUB604
local.identifier.citationvolume6
local.identifier.doi10.4161/cib.23653
local.identifier.scopusID2-s2.0-84879085255
local.identifier.thomsonIDMEDLINE:23710276
local.identifier.uidSubmittedBya383154
local.type.statusPublished Version

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