The solute carrier 6 family of transporters

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dc.contributor.authorBröer, Stefan
dc.contributor.authorGether, Ulrik
dc.date.accessioned2014-08-21T00:20:04Z
dc.date.available2014-08-21T00:20:04Z
dc.date.issued2012-09
dc.date.updated2015-12-08T02:42:35Z
dc.description.abstractThe solute carrier 6 (SLC6) family of the human genome comprises transporters for neurotransmitters, amino acids, osmolytes and energy metabolites. Members of this family play critical roles in neurotransmission, cellular and whole body homeostasis. Malfunction or altered expression of these transporters is associated with a variety of diseases. Pharmacological inhibition of the neurotransmitter transporters in this family is an important strategy in the management of neurological and psychiatric disorders. This review provides an overview of the biochemical and pharmacological properties of the SLC6 family transporters.
dc.format23 pages
dc.identifier.issn0007-1188
dc.identifier.urihttp://hdl.handle.net/1885/11958
dc.publisherWiley
dc.relationhttp://purl.org/au-research/grants/nhmrc/525415
dc.relationhttp://purl.org/au-research/grants/nhmrc/585479
dc.rights© 2012 The Authors
dc.sourceBritish Journal of Pharmacology 167.2 (2012):256-78
dc.subjectmonoamine transporters
dc.subjectantidepressants
dc.subjecttransport mechanism
dc.subjecttransporter pharmacology
dc.titleThe solute carrier 6 family of transporters
dc.typeJournal article
local.bibliographicCitation.lastpage278
local.bibliographicCitation.startpage256
local.contributor.affiliationBröer, Stefan, The Australian National Universityen_AU
local.contributor.authoruidu4009041en_AU
local.identifier.absfor110199 - Medical Biochemistry and Metabolomics not elsewhere classified
local.identifier.absseo970106 - Expanding Knowledge in the Biological Sciences
local.identifier.ariespublicationu4008405xPUB2
local.identifier.citationvolume167
local.identifier.doi10.1111/j.1476-5381.2012.01975.x
local.identifier.essn1476-5381en_AU
local.identifier.scopusID2-s2.0-84865425436
local.publisher.urlhttp://au.wiley.com/en_AU
local.type.statusPublished Versionen_AU

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