The application of a monolithic triphenylphosphine reagent for conducting Appel reactions in flow microreactors

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dc.contributor.authorRoper, Kimberley A
dc.contributor.authorLange, Heiko
dc.contributor.authorPolyzos, Anastasios
dc.contributor.authorBerry, Malcolm B
dc.contributor.authorBaxendale, Ian R
dc.contributor.authorLey, Steven V
dc.date.accessioned2016-03-21T22:59:53Z
dc.date.available2016-03-21T22:59:53Z
dc.date.issued2011-12-08
dc.description.abstractHerein we describe the application of a monolithic triphenylphosphine reagent to the Appel reaction in flow-chemistry processing, to generate various brominated products with high purity and in excellent yields, and with no requirement for further off-line purification.en_AU
dc.description.sponsorshipWe thank GlaxoSmithKline (Stevenage) for studentship support (KAR), the Alexander von Humboldt Foundation (HL), the EPSRC (KAR & TP), the Royal Society University Research Fellowship (IRB) and the BP 1702 Fellowship (SVL) for financial support.en_AU
dc.identifier.issn1860-5397en_AU
dc.identifier.urihttp://hdl.handle.net/1885/100843
dc.publisherBeilstein-Instituten_AU
dc.rights© 2011 Roper et al; licensee Beilstein-Institut. This is an Open Access article under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (http://www.beilstein-journals.org/bjoc)en_AU
dc.sourceBeilstein Journal of Organic Chemistryen_AU
dc.subjectappel reactionen_AU
dc.subjectbrominationen_AU
dc.subjectflow chemistryen_AU
dc.subjectsolid-supported reagenten_AU
dc.subjecttriphenylphosphine monolithen_AU
dc.titleThe application of a monolithic triphenylphosphine reagent for conducting Appel reactions in flow microreactorsen_AU
dc.typeJournal articleen_AU
dcterms.accessRightsOpen Accessen_AU
dcterms.dateAccepted2011-11-16
local.bibliographicCitation.lastpage1655en_AU
local.bibliographicCitation.startpage1648en_AU
local.contributor.affiliationRoper, Kimberley, College of Physical and Mathematical Sciences, CPMS Research School of Chemistry, RSC General, The Australian National Universityen_AU
local.contributor.affiliationLange, Heiko, University of Cambridge, United Kingdomen_AU
local.contributor.affiliationPolyzos, Anastasios, University of Cambridge, United Kingdomen_AU
local.contributor.affiliationBerry, Malcolm B., GlaxoSmithKline, United Kingdomen_AU
local.contributor.affiliationBaxendale, Ian R., University of Cambridge, United Kingdomen_AU
local.contributor.affiliationLey, Steven V., University of Cambridge, United Kingdomen_AU
local.contributor.authoremailkimberley.roper@anu.edu.auen_AU
local.contributor.authoruidu5424041en_AU
local.description.notesImported from ARIESen_AU
local.identifier.absfor030503en_AU
local.identifier.absseo970103en_AU
local.identifier.ariespublicationu4005981xPUB789en_AU
local.identifier.citationvolume7en_AU
local.identifier.doi10.3762/bjoc.7.194en_AU
local.identifier.essn1860-5397en_AU
local.identifier.uidSubmittedByu3488905en_AU
local.publisher.urlhttp://www.beilstein-institut.de/en/homeen_AU
local.type.statusPublished Versionen_AU

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