Permeation Dynamics of Chloride Ions in the CIC-O and CIC-1 Channels
dc.contributor.author | Corry, Ben | |
dc.contributor.author | O'Mara, Megan | |
dc.contributor.author | Chung, Shin-Ho | |
dc.date.accessioned | 2015-12-13T22:40:18Z | |
dc.date.available | 2015-12-13T22:40:18Z | |
dc.date.issued | 2004 | |
dc.date.updated | 2015-12-11T09:55:00Z | |
dc.description.abstract | We examine the mechanisms underlying the transport of ions across ClC-0 and ClC-1, the two best characterized members of the ubiquitous ClC chloride channel family. Using molecular and Brownian dynamics techniques we create an open channel structure, deduce the permeation characteristics, and highlight the amino acid residues responsible for the different conductance properties of these channels. | |
dc.identifier.issn | 0009-2614 | |
dc.identifier.uri | http://hdl.handle.net/1885/78176 | |
dc.publisher | Elsevier | |
dc.source | Chemical Physics Letters | |
dc.subject | Keywords: amino acid; chloride ion; article; chemical analysis; chemical structure; chloride channel; controlled study; ion conductance; ion transport; molecular dynamics; nonhuman; structure analysis | |
dc.title | Permeation Dynamics of Chloride Ions in the CIC-O and CIC-1 Channels | |
dc.type | Journal article | |
local.bibliographicCitation.lastpage | 238 | |
local.bibliographicCitation.startpage | 233 | |
local.contributor.affiliation | Corry, Ben, College of Physical and Mathematical Sciences, ANU | |
local.contributor.affiliation | O'Mara, Megan, College of Physical and Mathematical Sciences, ANU | |
local.contributor.affiliation | Chung, Shin-Ho, College of Physical and Mathematical Sciences, ANU | |
local.contributor.authoremail | u9719358@anu.edu.au | |
local.contributor.authoruid | Corry, Ben, u9719358 | |
local.contributor.authoruid | O'Mara, Megan, u4022190 | |
local.contributor.authoruid | Chung, Shin-Ho, u8809509 | |
local.description.notes | Imported from ARIES | |
local.description.refereed | Yes | |
local.identifier.absfor | 029901 - Biological Physics | |
local.identifier.absfor | 060110 - Receptors and Membrane Biology | |
local.identifier.ariespublication | MigratedxPub6858 | |
local.identifier.citationvolume | 386 | |
local.identifier.doi | 10.1016/j.cplett.2004.01.072 | |
local.identifier.scopusID | 2-s2.0-1442360876 | |
local.identifier.uidSubmittedBy | Migrated | |
local.type.status | Published Version |