Dealing with intractable protein cores: protein sequencing of the Mcg IgG and the Yvo IgM heavy chain variable domains
| dc.contributor.author | Shaw, Denis | |
| dc.contributor.author | Shultz, Brandon | |
| dc.contributor.author | Ramsland, Paul | |
| dc.contributor.author | Edmundson, Allen | |
| dc.date.accessioned | 2015-12-13T23:40:05Z | |
| dc.date.available | 2015-12-13T23:40:05Z | |
| dc.date.issued | 2002 | |
| dc.date.updated | 2015-12-12T09:27:44Z | |
| dc.description.abstract | The VH domains of two human monoclonal antibodies, designated Mcg IgGI(λ) and Yvo IgM(κ), were particularly intractable to standard protein sequencing protocols. Peptides liberated from the VH domains of these proteins, using standard enzymatic or chemi | |
| dc.identifier.issn | 0952-3499 | |
| dc.identifier.uri | http://hdl.handle.net/1885/94297 | |
| dc.publisher | John Wiley & Sons Inc | |
| dc.source | Journal of Molecular Recognition | |
| dc.subject | Keywords: dodecyl sulfate sodium; immunoglobulin G; immunoglobulin heavy chain; monoclonal antibody; Bence Jones protein; immunoglobulin; immunoglobulin M; myeloma immunoglobulins; paraprotein; amino acid sequence; polyacrylamide gel electrophoresis; protein degrad Antibody crystallography; Human monoclonal antibodies; Insoluble peptides; Protein sequencing | |
| dc.title | Dealing with intractable protein cores: protein sequencing of the Mcg IgG and the Yvo IgM heavy chain variable domains | |
| dc.type | Journal article | |
| local.bibliographicCitation.lastpage | 348 | |
| local.bibliographicCitation.startpage | 341 | |
| local.contributor.affiliation | Shaw, Denis, College of Medicine, Biology and Environment, ANU | |
| local.contributor.affiliation | Shultz, Brandon, Oklahoma Medical Research Foundation | |
| local.contributor.affiliation | Ramsland, Paul, Austin Research Institute | |
| local.contributor.affiliation | Edmundson, Allen, Oklahoma Medical Research Foundation | |
| local.contributor.authoremail | repository.admin@anu.edu.au | |
| local.contributor.authoruid | Shaw, Denis, u7300864 | |
| local.description.notes | Imported from ARIES | |
| local.description.refereed | Yes | |
| local.identifier.absfor | 110106 - Medical Biochemistry: Proteins and Peptides (incl. Medical Proteomics) | |
| local.identifier.ariespublication | MigratedxPub23857 | |
| local.identifier.citationvolume | 15 | |
| local.identifier.doi | 10.1002/jmr.596 | |
| local.identifier.scopusID | 2-s2.0-0036761294 | |
| local.identifier.uidSubmittedBy | Migrated | |
| local.type.status | Published Version |