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Single molecule characterization of the interactions between amyloid-β peptides and the membranes of hippocampal cells

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dc.contributor.authorNarayan, Priyanka
dc.contributor.authorGanzinger, Kristina A.
dc.contributor.authorMcColl, James
dc.contributor.authorWeimann, Laura
dc.contributor.authorMeehan, Sarah
dc.contributor.authorQamar, Seema
dc.contributor.authorCarver, John
dc.contributor.authorWilson, Mark
dc.contributor.authorSt. George-Hyslop, Peter
dc.contributor.authorDobson, Christopher M.
dc.contributor.authorKlenerman, David
dc.date.accessioned2015-12-10T23:04:06Z
dc.date.issued2013
dc.date.updated2016-02-24T10:25:45Z
dc.description.abstractOligomers of the 40 and 42 residue amyloid-β peptides (Aβ40 and Aβ42) have been implicated in the neuronal damage and impaired cognitive function associated with Alzheimer's disease. However, little is known about the specific mechanisms by which these
dc.identifier.issn0002-7863
dc.identifier.urihttp://hdl.handle.net/1885/62225
dc.publisherAmerican Chemical Society
dc.sourceJournal of the American Chemical Society
dc.subjectKeywords: Alzheimer's disease; Cell surfaces; Cellular response; Cognitive functions; Hippocampal cells; Live cell; Molecular chaperones; Nanomolar concentration; Neuronal cell; Neuronal damage; Protein aggregates; Quantitative study; Sensitive method; Single-molec
dc.titleSingle molecule characterization of the interactions between amyloid-β peptides and the membranes of hippocampal cells
dc.typeJournal article
local.bibliographicCitation.issue4
local.bibliographicCitation.lastpage1498
local.bibliographicCitation.startpage1491
local.contributor.affiliationNarayan, Priyanka, University of Cambridge
local.contributor.affiliationGanzinger, Kristina A., University of Cambridge
local.contributor.affiliationMcColl, James, University of Cambridge
local.contributor.affiliationWeimann, Laura, University of Cambridge
local.contributor.affiliationMeehan, Sarah, University of Cambridge
local.contributor.affiliationQamar, Seema, Cambridge Institute for Medical Research
local.contributor.affiliationCarver, John, College of Physical and Mathematical Sciences, ANU
local.contributor.affiliationWilson, Mark, University of Wollongong
local.contributor.affiliationSt. George-Hyslop, Peter, Cambridge Institute for Medical Research
local.contributor.affiliationDobson, Christopher M., University of Cambridge
local.contributor.affiliationKlenerman, David, University of Cambridge
local.contributor.authoruidCarver, John, u1571001
local.description.embargo2037-12-31
local.description.notesImported from ARIES
local.identifier.absfor030406 - Proteins and Peptides
local.identifier.absseo970103 - Expanding Knowledge in the Chemical Sciences
local.identifier.ariespublicationu4005981xPUB678
local.identifier.citationvolume135
local.identifier.doi10.1021/ja3103567
local.identifier.scopusID2-s2.0-84873809834
local.identifier.thomsonID000314492500052
local.type.statusPublished Version

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