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Modeling the Impact of DNA Methylation on the Evolution of BRCA1 in Mammals

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dc.contributor.authorHuttley, Gavin Austin
dc.date.accessioned2015-12-13T22:39:46Z
dc.date.available2015-12-13T22:39:46Z
dc.date.issued2004
dc.date.updated2015-12-11T09:52:07Z
dc.description.abstractThe modified base 5-methylcytosine (mC) plays an important functional role in the biology of mammals as an epigenetic modification and appears to exert a striking impact on the molecular evolution of mammal genomes. The collective epigenetic functions of
dc.identifier.issn0737-4038
dc.identifier.urihttp://hdl.handle.net/1885/77923
dc.publisherSociety for Molecular Biology Evolution
dc.sourceMolecular Biology and Evolution
dc.subjectKeywords: 5 methylcytosine; BRCA1 protein; dinucleotide; DNA; nucleotide; article; codon; codon substitution; CpG island; DNA methylation; DNA sequence; exon; gene mutation; mammal; maximum likelihood method; molecular evolution; molecular model; nonhuman; nucleoti BRCA1; Codon substitution model; CpG; DNA methylation; Maximum-likelihood; Molecular evolution
dc.titleModeling the Impact of DNA Methylation on the Evolution of BRCA1 in Mammals
dc.typeJournal article
local.bibliographicCitation.issue9
local.bibliographicCitation.lastpage1768
local.bibliographicCitation.startpage1760
local.contributor.affiliationHuttley, Gavin Austin, College of Medicine, Biology and Environment, ANU
local.contributor.authoruidHuttley, Gavin Austin, u9800703
local.description.notesImported from ARIES
local.description.refereedYes
local.identifier.absfor060409 - Molecular Evolution
local.identifier.absfor010401 - Applied Statistics
local.identifier.ariespublicationMigratedxPub6653
local.identifier.citationvolume21
local.identifier.doi10.1093/molbev/msh187
local.identifier.scopusID2-s2.0-4143132023
local.type.statusPublished Version

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