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Cell surface-expressed cation-independent mannose 6-phosphate receptor (CD222) binds enzymatically active heparanase independently of mannose 6-phosphate to promote extracellular matrix degradation

dc.contributor.authorWood, Robert
dc.contributor.authorHulett, Mark
dc.date.accessioned2015-12-08T22:23:50Z
dc.date.issued2008
dc.date.updated2015-12-08T08:55:27Z
dc.description.abstractHeparanase is a β-D-endoglucuronidase that cleaves heparan sulfate, an important structural component of the extracellular matrix (ECM) and vascular basement membrane (BM). The cleavage of heparan sulfate by heparanase-expressing cells, such as activated
dc.identifier.issn0021-9258
dc.identifier.urihttp://hdl.handle.net/1885/33038
dc.publisherAmerican Society for Biochemistry and Molecular Biology Inc
dc.sourceJournal of Biological Chemistry
dc.subjectKeywords: Adhesion; Cell adhesion; Cell culture; Cell membranes; Cytology; Degradation; Electric discharge machining; Endothelial cells; Enzyme inhibition; Pathology; Positive ions; Tumors; Acidic ph; Angiogenesis; Basement membranes; Cell invasions; Cell lines; Ce
dc.titleCell surface-expressed cation-independent mannose 6-phosphate receptor (CD222) binds enzymatically active heparanase independently of mannose 6-phosphate to promote extracellular matrix degradation
dc.typeJournal article
local.bibliographicCitation.issue7
local.bibliographicCitation.lastpage76
local.bibliographicCitation.startpage4165
local.contributor.affiliationWood, Robert, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationHulett, Mark, College of Medicine, Biology and Environment, ANU
local.contributor.authoruidWood, Robert, u4041796
local.contributor.authoruidHulett, Mark, a261320
local.description.embargo2037-12-31
local.description.notesImported from ARIES
local.identifier.absfor060110 - Receptors and Membrane Biology
local.identifier.ariespublicationu4020362xPUB98
local.identifier.citationvolume283
local.identifier.doi10.1074/jbc.M708723200
local.identifier.scopusID2-s2.0-42949156428
local.type.statusPublished Version

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