The accumulation of circulating histones on heparan sulphate in the capillary glycocalyx of the lungs

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dc.contributor.authorFreeman, Craigen_AU
dc.contributor.authorKnox, Karenen_AU
dc.contributor.authorBell, Jessicaen_AU
dc.contributor.authorLobov, Sergeyen_AU
dc.contributor.authorKing, Daviden_AU
dc.contributor.authorSenden, Timothyen_AU
dc.contributor.authorStephens, Rossen_AU
dc.contributor.authorParish, Christopheren_AU
dc.date.accessioned2015-12-13T22:23:16Z
dc.date.issued2013
dc.date.updated2016-02-24T09:10:23Z
dc.description.abstractRecent findings on the role of circulating histone proteins in mediating acute lung injury prompted us to investigate whether there is a specific mechanism for accumulation of histones in the lungs. Binding sites for polycations are already known in the v
dc.identifier.issn0142-9612
dc.identifier.urihttp://hdl.handle.net/1885/72692
dc.publisherPergamon-Elsevier Ltd
dc.sourceBiomaterials
dc.subjectKeywords: Acute lung injury; Biodistributions; Charge interactions; Heparan sulphate; Histones; Intravenous injections; Lung endothelium; Positively charged; Amino acids; Biological organs; Blood vessels; Imaging techniques; Sulfur compounds; Proteins; heparan sulf Acute lung injury; Heparan sulphate; Histones; Lung endothelium
dc.titleThe accumulation of circulating histones on heparan sulphate in the capillary glycocalyx of the lungs
dc.typeJournal article
local.bibliographicCitation.issue22
local.bibliographicCitation.lastpage5676
local.bibliographicCitation.startpage5670
local.contributor.affiliationFreeman, Craig, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationParish, Christopher, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationKnox, Karen, College of Physical and Mathematical Sciences, ANU
local.contributor.affiliationBell, Jessica, College of Physical and Mathematical Sciences, ANU
local.contributor.affiliationLobov, Sergey, College of Physical and Mathematical Sciences, ANU
local.contributor.affiliationKing, David, College of Physical and Mathematical Sciences, ANU
local.contributor.affiliationSenden, Timothy , College of Physical and Mathematical Sciences, ANU
local.contributor.affiliationStephens, Ross, College of Physical and Mathematical Sciences, ANU
local.contributor.authoruidFreeman, Craig, u9113554
local.contributor.authoruidParish, Christopher, u6900322
local.contributor.authoruidKnox, Karen, u4559237
local.contributor.authoruidBell, Jessica, u5132461
local.contributor.authoruidLobov, Sergey, u4910307
local.contributor.authoruidKing, David, u4287850
local.contributor.authoruidSenden, Timothy , u8612475
local.contributor.authoruidStephens, Ross, u4168074
local.description.embargo2037-12-31
local.description.notesImported from ARIES
local.identifier.absfor110203 - Respiratory Diseases
local.identifier.absfor110202 - Haematology
local.identifier.absseo920109 - Infectious Diseases
local.identifier.absseo920115 - Respiratory System and Diseases (incl. Asthma)
local.identifier.ariespublicationf5625xPUB3383
local.identifier.citationvolume34
local.identifier.doi10.1016/j.biomaterials.2013.03.091
local.identifier.scopusID2-s2.0-84877629429
local.identifier.thomsonID000319855600023
local.type.statusPublished Version

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