The accumulation of circulating histones on heparan sulphate in the capillary glycocalyx of the lungs

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Authors

Freeman, Craig
Knox, Karen
Bell, Jessica
Lobov, Sergey
King, David
Senden, Timothy
Stephens, Ross
Parish, Christopher

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Pergamon-Elsevier Ltd

Abstract

Recent findings on the role of circulating histone proteins in mediating acute lung injury prompted us to investigate whether there is a specific mechanism for accumulation of histones in the lungs. Binding sites for polycations are already known in the v

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Citation

Source

Biomaterials

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Restricted until

2037-12-31