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B7-H1 Blockade Increases Survival of Dysfunctional CD8+ T Cells and Confers Protection against Leishmania donovani Infections

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dc.contributor.authorJoshi, Trupti
dc.contributor.authorRodriguez, Susana
dc.contributor.authorPerovic, Vladimir
dc.contributor.authorCockburn, Ian
dc.contributor.authorStager, Simona
dc.date.accessioned2015-12-08T22:25:44Z
dc.date.issued2009
dc.date.updated2016-02-24T12:02:35Z
dc.description.abstractExperimental visceral leishmaniasis (VL) represents an exquisite model to study CD8+ T cell responses in a context of chronic inflammation and antigen persistence, since it is characterized by chronic infection in the spleen and CD8+ T cells are required
dc.identifier.issn1553-7366
dc.identifier.urihttp://hdl.handle.net/1885/33586
dc.publisherPublic Library of Science
dc.sourcePLoS Pathogens
dc.subjectKeywords: b7 h1 antigen; lymphocyte antigen; ovalbumin; unclassified drug; B7 antigen; leukocyte antigen; membrane protein; OVA 8; OVA-8; Pdcd1lg1 protein, mouse; peptide; peptide fragment; animal cell; animal experiment; animal model; article; body burden; CD8+ T
dc.titleB7-H1 Blockade Increases Survival of Dysfunctional CD8+ T Cells and Confers Protection against Leishmania donovani Infections
dc.typeJournal article
local.bibliographicCitation.issue5
local.bibliographicCitation.startpagee1000431
local.contributor.affiliationJoshi, Trupti, Johns Hopkins University
local.contributor.affiliationRodriguez, Susana, Johns Hopkins University
local.contributor.affiliationPerovic, Vladimir, Johns Hopkins University
local.contributor.affiliationCockburn, Ian, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationStager, Simona, Johns Hopkins University
local.contributor.authoruidCockburn, Ian, u5289297
local.description.embargo2037-12-31
local.description.notesImported from ARIES
local.identifier.absfor110309 - Infectious Diseases
local.identifier.absfor110704 - Cellular Immunology
local.identifier.absseo920109 - Infectious Diseases
local.identifier.absseo920108 - Immune System and Allergy
local.identifier.ariespublicationu9505948xPUB103
local.identifier.citationvolume5
local.identifier.doi10.1371/journal.ppat.1000431
local.identifier.scopusID2-s2.0-67249117672
local.type.statusPublished Version

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