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B7-H1 Blockade Increases Survival of Dysfunctional CD8+ T Cells and Confers Protection against Leishmania donovani Infections

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Authors

Joshi, Trupti
Rodriguez, Susana
Perovic, Vladimir
Cockburn, Ian
Stager, Simona

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Volume Title

Publisher

Public Library of Science

Abstract

Experimental visceral leishmaniasis (VL) represents an exquisite model to study CD8+ T cell responses in a context of chronic inflammation and antigen persistence, since it is characterized by chronic infection in the spleen and CD8+ T cells are required

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Source

PLoS Pathogens

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Restricted until

2037-12-31
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