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A DNA prime-live vaccine boost strategy in mice can augment IFN-γ responses to mycobacterial antigens but does not increase the protective efficacy of two attenuated strains of Mycobacterium bovis against bovine tuberculosis

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dc.contributor.authorSkinner, Margot Aen_AU
dc.contributor.authorRamsey, A Jen_AU
dc.contributor.authorBuchan, C Sen_AU
dc.contributor.authorKeen, D Len_AU
dc.contributor.authorSlobbe, Len_AU
dc.contributor.authorCollins, D Men_AU
dc.contributor.authorde Lisle, GWen_AU
dc.contributor.authorBuddle, B Men_AU
dc.contributor.authorRanasinghe, Charanien_AU
dc.date.accessioned2015-12-07T22:27:55Z
dc.date.issued2003
dc.date.updated2015-12-07T09:58:23Z
dc.description.abstractThe Mycobacterium bovis bacille Calmette-Guérin (BCG) vaccine has variable efficacy for both human and bovine tuberculosis. There is a need for improved vaccines or vaccine strategies for control of these diseases. A recently developed prime-boost strate
dc.identifier.issn0019-2805
dc.identifier.urihttp://hdl.handle.net/1885/22124
dc.publisherBlackwell Publishing Ltd
dc.sourceImmunology
dc.subjectKeywords: BCG vaccine; DNA vaccine; gamma interferon; immunoglobulin G1; live vaccine; Mycobacterium antigen; plasmid DNA; animal cell; animal model; antibody response; antigen expression; article; attenuation; bacterial strain; cattle disease; controlled study; cy
dc.titleA DNA prime-live vaccine boost strategy in mice can augment IFN-γ responses to mycobacterial antigens but does not increase the protective efficacy of two attenuated strains of Mycobacterium bovis against bovine tuberculosis
dc.typeJournal article
local.bibliographicCitation.issue4
local.bibliographicCitation.lastpage555
local.bibliographicCitation.startpage548
local.contributor.affiliationSkinner, Margot A, AgResearch
local.contributor.affiliationRamsey, A J, LSU Health Sciences Centre
local.contributor.affiliationBuchan, C S, University of Otago
local.contributor.affiliationKeen, D L, AgResearch
local.contributor.affiliationRanasinghe, Charani, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationSlobbe, L, University of Otago
local.contributor.affiliationCollins, D M, AgResearch
local.contributor.affiliationde Lisle, GW, Wallaceville Animal Research Centre
local.contributor.affiliationBuddle, B M, AgResearch
local.contributor.authoruidRanasinghe, Charani, u4107621
local.description.embargo2037-12-31
local.description.notesImported from ARIES
local.identifier.absfor100401 - Gene and Molecular Therapy
local.identifier.ariespublicationu4133361xPUB20
local.identifier.citationvolume108
local.identifier.doi10.1046/j.1365-2567.2003.01589.x
local.identifier.scopusID2-s2.0-0344406062
local.type.statusPublished Versionen_AU

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