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A DNA prime-live vaccine boost strategy in mice can augment IFN-γ responses to mycobacterial antigens but does not increase the protective efficacy of two attenuated strains of Mycobacterium bovis against bovine tuberculosis

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Date

2003

Authors

Skinner, Margot A
Ramsey, A J
Buchan, C S
Keen, D L
Slobbe, L
Collins, D M
de Lisle, GW
Buddle, B M
Ranasinghe, Charani

Journal Title

Journal ISSN

Volume Title

Publisher

Blackwell Publishing Ltd

Abstract

The Mycobacterium bovis bacille Calmette-Guérin (BCG) vaccine has variable efficacy for both human and bovine tuberculosis. There is a need for improved vaccines or vaccine strategies for control of these diseases. A recently developed prime-boost strate

Description

Keywords

Keywords: BCG vaccine; DNA vaccine; gamma interferon; immunoglobulin G1; live vaccine; Mycobacterium antigen; plasmid DNA; animal cell; animal model; antibody response; antigen expression; article; attenuation; bacterial strain; cattle disease; controlled study; cy

Citation

URI

http://hdl.handle.net/1885/22124

Collections

ANU Research Publications

Source

Immunology

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

10.1046/j.1365-2567.2003.01589.x

Restricted until

2037-12-31

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Description
01_Skinner_A_DNA_prime-live_vaccine_boost_2003.pdf (163.02 KB)

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