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Diverse chemotypes disrupt ion homeostasis in the malaria parasite

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dc.contributor.authorLehane, Adele
dc.contributor.authorRidgway, Melanie
dc.contributor.authorBaker, Eileen
dc.contributor.authorKirk, Kiaran
dc.date.accessioned2015-12-07T22:50:17Z
dc.date.issued2014
dc.date.updated2015-12-07T12:16:03Z
dc.description.abstractThe antimalarial spiroindolones disrupt Plasmodium falciparumNa+ regulation and induce an alkalinization of the parasite cytosol. It has been proposed that they do so by inhibiting PfATP4, a parasite plasma membrane P-type ATPase postulated to export Na+
dc.identifier.issn0950-382X
dc.identifier.urihttp://hdl.handle.net/1885/26961
dc.publisherBlackwell Publishing Ltd
dc.sourceMolecular Microbiology
dc.titleDiverse chemotypes disrupt ion homeostasis in the malaria parasite
dc.typeJournal article
local.bibliographicCitation.issue2
local.bibliographicCitation.lastpage339
local.bibliographicCitation.startpage327
local.contributor.affiliationLehane, Adele, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationRidgway, Melanie, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationBaker, Eileen, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationKirk, Kiaran, College of Medicine, Biology and Environment, ANU
local.contributor.authoruidLehane, Adele, u3356728
local.contributor.authoruidRidgway, Melanie, u5454069
local.contributor.authoruidBaker, Eileen, u4433239
local.contributor.authoruidKirk, Kiaran, u9608579
local.description.embargo2037-12-31
local.description.notesImported from ARIES
local.identifier.absfor060199 - Biochemistry and Cell Biology not elsewhere classified
local.identifier.absseo920109 - Infectious Diseases
local.identifier.ariespublicationu4008405xPUB48
local.identifier.citationvolume94
local.identifier.doi10.1111/mmi.12765
local.identifier.scopusID2-s2.0-84916599750
local.identifier.thomsonID000343755700007
local.type.statusPublished Version

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