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The Retinal G Protein-coupled Receptor (RGR) Enhances Isomerohydrolase Activity Independent of Light

dc.contributor.authorWenzel, Andreas
dc.contributor.authorOberhauser, Vitus
dc.contributor.authorPugh, Edward N
dc.contributor.authorLamb, Trevor
dc.contributor.authorGrimm, Christian
dc.contributor.authorSamardzija, Marijana
dc.contributor.authorFahl, Edda
dc.contributor.authorSeeliger, Mathius W
dc.contributor.authorReme, Charlotte E
dc.contributor.authorvon Lintig, Johannes
dc.date.accessioned2015-12-13T23:00:01Z
dc.date.issued2005
dc.date.updated2015-12-12T07:31:52Z
dc.description.abstractRod and cone visual pigments use 11-cis-retinal, a vitamin A derivative, as their chromophore. Light isomerizes 11-cis- into all-trans-retinal, triggering a conformational transition of the opsin molecule that initiates phototransduction. After bleaching
dc.identifier.issn0021-9258
dc.identifier.urihttp://hdl.handle.net/1885/83951
dc.publisherAmerican Society for Biochemistry and Molecular Biology Inc
dc.sourceJournal of Biological Chemistry
dc.subjectKeywords: Chromophores; Conformations; Pigments; Vitamins; Light isomerizes; Opsin molecule; Photoisomerase; Phototransduction; Proteins; 11 cis retinal; G protein coupled receptor; hydrolase; lsomerohydolase; opsin; retinal; retinal G protein coupled receptor; ret
dc.titleThe Retinal G Protein-coupled Receptor (RGR) Enhances Isomerohydrolase Activity Independent of Light
dc.typeJournal article
local.bibliographicCitation.issue33
local.bibliographicCitation.lastpage29884
local.bibliographicCitation.startpage29874
local.contributor.affiliationWenzel, Andreas, University Hospital Zurich
local.contributor.affiliationOberhauser, Vitus, University of Freiburg
local.contributor.affiliationPugh, Edward N, University of Pennsylvania
local.contributor.affiliationLamb, Trevor, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationGrimm, Christian, University Hospital Zurich
local.contributor.affiliationSamardzija, Marijana, University Hospital Zurich
local.contributor.affiliationFahl, Edda, University Eye Hospital Tuebingen
local.contributor.affiliationSeeliger, Mathius W, University Eye Hospital Tuebingen
local.contributor.affiliationReme, Charlotte E, University Hospital Zurich
local.contributor.affiliationvon Lintig, Johannes, University of Freiburg
local.contributor.authoruidLamb, Trevor, u4053601
local.description.embargo2037-12-31
local.description.notesImported from ARIES
local.description.refereedYes
local.identifier.absfor110906 - Sensory Systems
local.identifier.ariespublicationMigratedxPub12226
local.identifier.citationvolume280
local.identifier.doi10.1074/jbc.M503603200
local.identifier.scopusID2-s2.0-23844496400
local.type.statusPublished Version

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