The Retinal G Protein-coupled Receptor (RGR) Enhances Isomerohydrolase Activity Independent of Light
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Authors
Wenzel, Andreas
Oberhauser, Vitus
Pugh, Edward N
Lamb, Trevor
Grimm, Christian
Samardzija, Marijana
Fahl, Edda
Seeliger, Mathius W
Reme, Charlotte E
von Lintig, Johannes
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American Society for Biochemistry and Molecular Biology Inc
Abstract
Rod and cone visual pigments use 11-cis-retinal, a vitamin A derivative, as their chromophore. Light isomerizes 11-cis- into all-trans-retinal, triggering a conformational transition of the opsin molecule that initiates phototransduction. After bleaching
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Journal of Biological Chemistry
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2037-12-31
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