Activation of cathepsin D by glycosaminoglycans
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Beckman, Marie
Freeman, Craig
Small, David H
Parish, Christopher
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Blackwell Publishing Ltd
Abstract
We have previously shown that heparin can increase the activity of the proenzyme form of Alzheimer's β-site amyloid precursor protein cleaving enzyme 1 (BACE1). Cathepsin D (CD) is a member of the aspartic protease family and has sequence similarity to B
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The FEBS Journal
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2037-12-31
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