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The total synthesis of (−)-tetrahydrolipstatin (Short Communication)

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dc.contributor.authorBodkin, Jennifer A
dc.contributor.authorHumphries, Edward
dc.contributor.authorMcLeod, Malcolm
dc.date.accessioned2015-12-10T22:38:21Z
dc.date.issued2003
dc.date.updated2015-12-09T10:39:14Z
dc.description.abstractCareful control during the bromolactonisation of β,γ-unsaturated acid 3 was required to afford regioselectively the trans-β-lactone 4 as the major diastereomer. Radical debromination of 4 followed by a three-step sequence of reactions afforded the lipa
dc.identifier.issn0040-4039
dc.identifier.urihttp://hdl.handle.net/1885/56725
dc.publisherElsevier
dc.sourceTetrahedron Letters
dc.subjectKeywords: acid; lactone derivative; tetrahydrolipstatin; article; bromolactonization; chemical reaction; debromination; diastereoisomer; drug synthesis; proton nuclear magnetic resonance; stereochemistry ß-lactone; (-)-tetrahydrolipstatin; Bromolactonisation; Radical dehalogenation
dc.titleThe total synthesis of (−)-tetrahydrolipstatin (Short Communication)
dc.typeJournal article
local.bibliographicCitation.issue14
local.bibliographicCitation.lastpage2872
local.bibliographicCitation.startpage2869
local.contributor.affiliationBodkin, Jennifer A, University of Sydney
local.contributor.affiliationHumphries, Edward, University of Sydney
local.contributor.affiliationMcLeod, Malcolm, College of Physical and Mathematical Sciences, ANU
local.contributor.authoruidMcLeod, Malcolm, u4045340
local.description.embargo2037-12-31
local.description.notesImported from ARIES
local.identifier.absfor030503 - Organic Chemical Synthesis
local.identifier.ariespublicationu4005981xPUB373
local.identifier.citationvolume44
local.identifier.doi10.1016/S0040-4039(03)00443-X
local.identifier.scopusID2-s2.0-0037474670
local.type.statusPublished Version

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