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Analysis of Complement Expression in Light-Induced Retinal Degeneration: Synthesis and Deposition of C3 by Microglia/Macrophages Is Associated with Focal Photoreceptor Degeneration

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dc.contributor.authorRutar, Matthew
dc.contributor.authorNatoli, Riccardo
dc.contributor.authorKozulin, Peter
dc.contributor.authorValter (Valter-Kocsi), Krisztina
dc.contributor.authorGatenby, Paul
dc.contributor.authorProvis, Jan
dc.date.accessioned2015-12-10T22:15:40Z
dc.date.issued2011
dc.date.updated2016-02-24T11:41:30Z
dc.description.abstractPurpose. To investigate the expression and localization of complement system mRNA and protein in a light-induced model of progressive retinal degeneration. Methods. Sprague-Dawley (SD) rats were exposed to 1000 lux of bright continuous light (BCL) for up
dc.identifier.issn1552-5783
dc.identifier.urihttp://hdl.handle.net/1885/50796
dc.publisherAssociation for Research in Vision and Opthalmology
dc.rightsAuthor/s retain copyrighten_AU
dc.sourceInvestigative Ophthalmology and Visual Science
dc.subjectKeywords: complement component C1q; complement component C1r; complement component C1s; complement component C3; complement component C3 receptor; complement component C3a; complement component C4a; complement component C4b; decay accelerating factor; glyceraldehyd
dc.titleAnalysis of Complement Expression in Light-Induced Retinal Degeneration: Synthesis and Deposition of C3 by Microglia/Macrophages Is Associated with Focal Photoreceptor Degeneration
dc.typeJournal article
dcterms.accessRightsOpen Accessen_AU
local.bibliographicCitation.issue8
local.bibliographicCitation.lastpage5358
local.bibliographicCitation.startpage5347
local.contributor.affiliationRutar, Matthew, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationNatoli, Riccardo, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationKozulin, Peter, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationValter (Valter-Kocsi), Krisztina, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationGatenby, Paul, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationProvis, Jan, College of Medicine, Biology and Environment, ANU
local.contributor.authoruidRutar, Matthew, u4125807
local.contributor.authoruidNatoli, Riccardo, u4100537
local.contributor.authoruidKozulin, Peter, u4193734
local.contributor.authoruidValter (Valter-Kocsi), Krisztina, u4055998
local.contributor.authoruidGatenby, Paul, u4044018
local.contributor.authoruidProvis, Jan, u4118802
local.description.notesImported from ARIES
local.identifier.absfor111301 - Ophthalmology
local.identifier.ariespublicationu8611701xPUB210
local.identifier.citationvolume52
local.identifier.doi10.1167/iovs.10-7119
local.identifier.scopusID2-s2.0-80052920397
local.identifier.thomsonID000293377400045
local.type.statusPublished Version

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