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Analysis of Complement Expression in Light-Induced Retinal Degeneration: Synthesis and Deposition of C3 by Microglia/Macrophages Is Associated with Focal Photoreceptor Degeneration

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Date

2011

Authors

Rutar, Matthew
Natoli, Riccardo
Kozulin, Peter
Valter (Valter-Kocsi), Krisztina
Gatenby, Paul
Provis, Jan

Journal Title

Journal ISSN

Volume Title

Publisher

Association for Research in Vision and Opthalmology

Abstract

Purpose. To investigate the expression and localization of complement system mRNA and protein in a light-induced model of progressive retinal degeneration. Methods. Sprague-Dawley (SD) rats were exposed to 1000 lux of bright continuous light (BCL) for up

Description

Keywords

Keywords: complement component C1q; complement component C1r; complement component C1s; complement component C3; complement component C3 receptor; complement component C3a; complement component C4a; complement component C4b; decay accelerating factor; glyceraldehyd

Citation

URI

http://hdl.handle.net/1885/50796

Collections

ANU Research Publications

Source

Investigative Ophthalmology and Visual Science

Type

Journal article

Book Title

Entity type

Access Statement

Open Access

License Rights

DOI

10.1167/iovs.10-7119

Restricted until

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Description
01_Rutar_Analysis_of_Complement_2011.pdf (3.88 MB)

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