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How do glucocorticoids cause hypertension: Role of nitric oxide deficiency, oxidative stress, and eicosanoids

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dc.contributor.authorWhitworth, Judith
dc.contributor.authorOng, Lee Lin (Sharon)
dc.date.accessioned2015-12-10T23:35:31Z
dc.date.issued2011
dc.date.updated2016-02-24T08:22:32Z
dc.description.abstractThe exact mechanism by which glucocorticoid induces hypertension is unclear. Several mechanisms have been proposed, although there is evidence against the role of sodium and water retention as well as sympathetic nerve activation. This review highlights the role of nitric oxide-redox imbalance and their interactions with arachidonic acid metabolism in glucocorticoid-induced hypertension in humans and experimental animal models.
dc.identifier.issn0889-8529
dc.identifier.urihttp://hdl.handle.net/1885/69884
dc.publisherW B Saunders Co
dc.sourceEndocrinology and Metabolism Clinics of North America
dc.subjectKeywords: acetylcysteine; acetylsalicylic acid; angiotensin II; apocynin; arginine; argipressin; atenolol; atorvastatin; corticotropin; dexamethasone; endothelin; felodipine; folic acid; glucocorticoid; guanosine triphosphate cyclohydrolase I; hydrocortisone; icosa 20-hydroxyeicosatetranoic acid; Glucocorticoid; Hypertension; Nitric oxide; Oxidative stress; Prostanoids
dc.titleHow do glucocorticoids cause hypertension: Role of nitric oxide deficiency, oxidative stress, and eicosanoids
dc.typeJournal article
local.bibliographicCitation.issue2
local.bibliographicCitation.lastpage407
local.bibliographicCitation.startpage393
local.contributor.affiliationWhitworth, Judith, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationOng, Lee Lin (Sharon), University of Sydney
local.contributor.authoruidWhitworth, Judith, u9910403
local.description.embargo2037-12-31
local.description.notesImported from ARIES
local.identifier.absfor110306 - Endocrinology
local.identifier.ariespublicationf2965xPUB2149
local.identifier.citationvolume40
local.identifier.doi10.1016/j.ecl.2011.01.010
local.identifier.scopusID2-s2.0-79955726640
local.type.statusPublished Version

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