A minimum reporting standard for multiple sequence alignments
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Wong, Thomas
Kalyaanamoorthy, Subha
Meusemann, Karen
Yeates, David K.
Misof, Bernhard
Jermiin, Lars
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Oxford University Press
Abstract
Multiple sequence alignments (MSAs) play a pivotal role in studies of molecular sequence data, but nobody has developed a minimum reporting standard (MRS) to quantify the completeness of MSAs. We present an MRS that relies on four simple completeness metrics. The metrics are implemented in AliStat, a program developed to support the MRS. A survey of published MSAs illustrates the benefits and unprecedented transparency offered by the MRS.
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NAR Genomics and Bioinformatics
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Open Access
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Creative Commons Attribution Non-Commercial License
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