Cultural advice

The Australian National University acknowledges, celebrates and pays our respects to the Ngunnawal and Ngambri people of the Canberra region and to all First Nations Australians on whose traditional lands we meet and work, and whose cultures are among the oldest continuing cultures in human history.

Aboriginal and Torres Strait Islander peoples are advised that ANU Library collections may include images, names, voices, and other representations of deceased persons.

Material in the collection may contain terms, language or views that reflect the period in which the item was created and may be considered inappropriate today.

The fumagillin biosynthetic gene cluster in Aspergillus fumigatus encodes a cryptic terpene cyclase involved in the formation of -trans-bergamotene

Simple item page
dc.contributor.authorLin, Hsiao-Ching
dc.contributor.authorChooi, Yit-Heng
dc.contributor.authorDhingra, Sourabh
dc.contributor.authorXu, Wei
dc.contributor.authorCalvo, Ana M
dc.contributor.authorTang, Yi
dc.date.accessioned2015-12-13T22:52:12Z
dc.date.issued2013
dc.date.updated2016-02-24T09:46:18Z
dc.description.abstractFumagillin 1 is a meroterpenoid from Aspergillus fumigatus that is known for its anti-angiogenic activity by binding to human methionine aminopeptidase 2. The genetic and molecular basis for biosynthesis of 1 had been an enigma despite the availability of
dc.identifier.issn0002-7863
dc.identifier.urihttp://hdl.handle.net/1885/81463
dc.publisherAmerican Chemical Society
dc.sourceJournal of the American Chemical Society
dc.subjectKeywords: Acyltransferase; Anti-angiogenic activity; Aspergillus fumigatus; Biosynthetic gene cluster; Genome sequences; Methionine aminopeptidase; Molecular basis; Polyketide synthases; Amino acids; Aspergillus; Biochemistry; Biosynthesis; Plants (botany); Terpene
dc.titleThe fumagillin biosynthetic gene cluster in Aspergillus fumigatus encodes a cryptic terpene cyclase involved in the formation of -trans-bergamotene
dc.typeJournal article
local.bibliographicCitation.issue12
local.bibliographicCitation.lastpage4619
local.bibliographicCitation.startpage4616
local.contributor.affiliationLin, Hsiao-Ching, University of California
local.contributor.affiliationChooi, Yit-Heng, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationDhingra, Sourabh, Northern Illinois University
local.contributor.affiliationXu, Wei, University of California
local.contributor.affiliationCalvo, Ana M, Northern Illinois University
local.contributor.affiliationTang, Yi, University of California
local.contributor.authoruidChooi, Yit-Heng, u5418153
local.description.embargo2037-12-31
local.description.notesImported from ARIES
local.identifier.absfor060705 - Plant Physiology
local.identifier.absseo970106 - Expanding Knowledge in the Biological Sciences
local.identifier.ariespublicationf5625xPUB9754
local.identifier.citationvolume135
local.identifier.doi10.1021/ja312503y
local.identifier.scopusID2-s2.0-84875749007
local.identifier.thomsonID000317032000011
local.type.statusPublished Version

Downloads

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
01_Lin_The_fumagillin_biosynthetic_2013.pdf
Size:
1.25 MB
Format:
Adobe Portable Document Format
Download

Collections

ANU Research Publications

DSpace software copyright © 2002-2026 LYRASIS