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Germinal Center Lymphocyte Ratios and Successful HIV Vaccines

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dc.contributor.authorGonzalez-Figueroa, Paula
dc.contributor.authorRoco, Jonathan
dc.contributor.authorVinuesa, Carola
dc.date.accessioned2021-06-29T01:59:25Z
dc.date.issued2017
dc.date.updated2020-11-23T10:35:29Z
dc.description.abstractCurrent HIV vaccines are poor inducers of neutralizing antibodies (nAbs). A recent study in Cell Reports used serial fine-needle aspirates from rhesus macaque lymph nodes following HIV-1 surface envelope glycoprotein (Env) trimer immunization, generating a substantial production of HIV-1 nAbs. A remarkable correlation was found between antibody titers and a high frequency and ratio of germinal center B and T follicular helper (TFH) lymphocytes.en_AU
dc.description.sponsorshipC.G.V. is funded by the National Health and Medical Research Council (NHMRC) of Australiaen_AU
dc.format.mimetypeapplication/pdfen_AU
dc.identifier.issn1471-4914en_AU
dc.identifier.urihttp://hdl.handle.net/1885/238327
dc.language.isoen_AUen_AU
dc.publisherElsevieren_AU
dc.rights© 2017 Elsevieren_AU
dc.sourceTrends in Molecular Medicineen_AU
dc.titleGerminal Center Lymphocyte Ratios and Successful HIV Vaccinesen_AU
dc.typeJournal articleen_AU
local.bibliographicCitation.issue2en_AU
local.bibliographicCitation.lastpage97en_AU
local.bibliographicCitation.startpage95en_AU
local.contributor.affiliationGonzalez Figueroa, Paula, College of Health and Medicine, ANUen_AU
local.contributor.affiliationRoco, Jonathan, College of Health and Medicine, ANUen_AU
local.contributor.affiliationGarcia De Vinuesa, Maria Carola, College of Health and Medicine, ANUen_AU
local.contributor.authoruidGonzalez Figueroa, Paula, u5484276en_AU
local.contributor.authoruidRoco, Jonathan, u5484264en_AU
local.contributor.authoruidGarcia De Vinuesa, Maria Carola, u4164556en_AU
local.description.embargo2099-12-31
local.description.notesImported from ARIESen_AU
local.identifier.absfor110704 - Cellular Immunologyen_AU
local.identifier.absfor110705 - Humoural Immunology and Immunochemistryen_AU
local.identifier.absseo920108 - Immune System and Allergyen_AU
local.identifier.ariespublicationa383154xPUB4760en_AU
local.identifier.citationvolume23en_AU
local.identifier.doi10.1016/1.molmed.2016.12.009en_AU
local.identifier.scopusID2-s2.0-85009469932
local.identifier.thomsonID000397143100001
local.publisher.urlhttp://www.elsevier.com/wps/product/cws_home/30772/descriptionen_AU
local.type.statusPublished Versionen_AU

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