Skip navigation
Skip navigation

Islet β cell failure in type 2 diabetes

Prentki, M.; Nolan, C.


The major focus of this Review is on the mechanisms of islet beta cell failure in the pathogenesis of obesity-associated type 2 diabetes (T2D). As this demise occurs within the context of beta cell compensation for insulin resistance, consideration is also given to the mechanisms involved in the compensation process, including mechanisms for expansion of beta cell mass and for enhanced beta cell performance. The importance of genetic, intrauterine, and environmental factors in the determination...[Show more]

CollectionsANU Research Publications
Date published: 2006-07-03
Type: Journal article
Source: Journal of Clinical Investigation
DOI: 10.1172/JCI29103


File Description SizeFormat Image
01_Prentki_Islet_ _cell_failure_in_type_2_2006.pdfPublished Version704.88 kBAdobe PDFThumbnail

Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  20 July 2017/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator