Autophagy-independent functions of UVRAG are essential for peripheral naive T-cell homeostasis
Date
2015
Authors
Afzal, Samia
Hao, Zhenyue
Itsumi, Momoe
Abouelkheer, Yasser
Brenner, Dirk
Gao, Yunfei
Wakeham, Andrew
Hong, Claire
Li, Wanda Y
Sylvester, Jennifer
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National Academy of Sciences (USA)
Abstract
UV radiation resistance-associated gene (UVRAG) encodes a tumor suppressor with putative roles in autophagy, endocytic trafficking, and DNA damage repair but its in vivo role in T cells is unknown. Because conditional homozygous deletion of Uvrag in mice
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PNAS - Proceedings of the National Academy of Sciences of the United States of America
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Journal article
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Open Access
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Restricted until
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