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Autophagy-independent functions of UVRAG are essential for peripheral naive T-cell homeostasis

Afzal, Samia; Hao, Zhenyue; Itsumi, Momoe; Abouelkheer, Yasser; Brenner, Dirk; Gao, Yunfei; Wakeham, Andrew; Hong, Claire; Li, Wanda Y; Sylvester, Jennifer; Gilani, SO; Bruestle, Anne; Haight, J; You-Ten, A; Lin, GH; Inoue, Satoshi; Mak, Tak W

Description

UV radiation resistance-associated gene (UVRAG) encodes a tumor suppressor with putative roles in autophagy, endocytic trafficking, and DNA damage repair but its in vivo role in T cells is unknown. Because conditional homozygous deletion of Uvrag in mice

CollectionsANU Research Publications
Date published: 2015
Type: Journal article
URI: http://hdl.handle.net/1885/64334
Source: PNAS - Proceedings of the National Academy of Sciences of the United States of America
DOI: 10.1073/pnas.1423588112

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