Autophagy-independent functions of UVRAG are essential for peripheral naive T-cell homeostasis
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Afzal, Samia; Hao, Zhenyue; Itsumi, Momoe; Abouelkheer, Yasser; Brenner, Dirk; Gao, Yunfei; Wakeham, Andrew; Hong, Claire; Li, Wanda Y; Sylvester, Jennifer; Gilani, SO; Bruestle, Anne; Haight, J; You-Ten, A; Lin, GH; Inoue, Satoshi; Mak, Tak W
Description
UV radiation resistance-associated gene (UVRAG) encodes a tumor suppressor with putative roles in autophagy, endocytic trafficking, and DNA damage repair but its in vivo role in T cells is unknown. Because conditional homozygous deletion of Uvrag in mice
| Collections | ANU Research Publications |
|---|---|
| Date published: | 2015 |
| Type: | Journal article |
| URI: | http://hdl.handle.net/1885/64334 |
| Source: | PNAS - Proceedings of the National Academy of Sciences of the United States of America |
| DOI: | 10.1073/pnas.1423588112 |
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| File | Description | Size | Format | Image |
|---|---|---|---|---|
| 01_Afzal_Autophagy-independent_2015.pdf | 1.16 MB | Adobe PDF |
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