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Computer Simulation of Biological Ion Channels

Hoyles, Matthew


This thesis describes a project in which algorithms are developed for the rapid and accurate solution of Poisson's equation in the presence of a dielectric boundary and multiple point charges. These algorithms are then used to perform Brownian dynamics simulations on realistic models of biological ion channels. An iterative method of solution, in which the dielectric boundary is tiled with variable sized surface charge sectors, provides the flexibility to deal with arbitrarily shaped...[Show more]

CollectionsOpen Access Theses
Date published: 1999-09
Type: Thesis (PhD)


File Description SizeFormat Image
01front.pdf69.37 kBAdobe PDFThumbnail
02whole.pdf1.56 MBAdobe PDFThumbnail
03Chapters1-4.pdf537.04 kBAdobe PDFThumbnail
04Chapters5-6.pdf757.58 kBAdobe PDFThumbnail
05Chapter7-Bibliography.pdf451.73 kBAdobe PDFThumbnail

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