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Molecular and cellular mechanisms in the viral exacerbation of asthma

Tauro, Sharyn; Su, Yung-Chang; Thomas, Sandra; Schwarze, Jurgen; Matthaei, Klaus; Townsend, Dijana; Simson, Ljubov; Tripp, Ralph A; Mahalingam, Suresh (Surendran)


The aetiology of asthma associated with viral infection is complex. The dynamics that contribute to disease pathogenesis are multifactorial and involve overlapping molecular and cellular mechanisms, particularly the immune response to respiratory virus infection or allergen sensitization. This review summarizes the evidence associated with factors that may contribute to the development or exacerbation of asthma including age, host factors, genetic polymorphisms, altered immune responses, and...[Show more]

CollectionsANU Research Publications
Date published: 2008
Type: Journal article
Source: Microbes and Infection
DOI: 10.1016/j.micinf.2008.07.037


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