Mclip: Motif detection based on cliques of gapped local profile-to-profile alignments
-
Altmetric Citations
Frickey, Tancred; Weiller, Georg
Description
Summary: A multitude of motif-finding tools have been published, which can generally be assigned to one of three classes: expectation-maximization, Gibbs-sampling or enumeration. Irrespective of this grouping, most motif detection tools only take into account similarities across ungapped sequence regions, possibly causing short motifs located peripherally and in varying distance to a 'core' motif to be missed. We present a new method, adding to the set of expectation-maximization approaches,...[Show more]
dc.contributor.author | Frickey, Tancred | |
---|---|---|
dc.contributor.author | Weiller, Georg | |
dc.date.accessioned | 2015-12-07T22:41:05Z | |
dc.identifier.issn | 1367-4803 | |
dc.identifier.uri | http://hdl.handle.net/1885/24149 | |
dc.description.abstract | Summary: A multitude of motif-finding tools have been published, which can generally be assigned to one of three classes: expectation-maximization, Gibbs-sampling or enumeration. Irrespective of this grouping, most motif detection tools only take into account similarities across ungapped sequence regions, possibly causing short motifs located peripherally and in varying distance to a 'core' motif to be missed. We present a new method, adding to the set of expectation-maximization approaches, that permits the use of gapped alignments for motif elucidation. | |
dc.publisher | Oxford University Press | |
dc.source | Bioinformatics | |
dc.subject | Keywords: Arabidopsis; article; computer interface; computer program; gene expression profiling; Internet; microarray analysis; nonhuman; priority journal; scoring system; sequence alignment; sequence analysis; Algorithms; Base Sequence; Molecular Sequence Data; Se | |
dc.title | Mclip: Motif detection based on cliques of gapped local profile-to-profile alignments | |
dc.type | Journal article | |
local.description.notes | Imported from ARIES | |
local.identifier.citationvolume | 23 | |
dc.date.issued | 2007 | |
local.identifier.absfor | 060407 - Genome Structure and Regulation | |
local.identifier.ariespublication | u9204316xPUB30 | |
local.type.status | Published Version | |
local.contributor.affiliation | Frickey, Tancred, College of Medicine, Biology and Environment, ANU | |
local.contributor.affiliation | Weiller, Georg, College of Medicine, Biology and Environment, ANU | |
local.description.embargo | 2037-12-31 | |
local.bibliographicCitation.issue | 4 | |
local.bibliographicCitation.startpage | 502 | |
local.bibliographicCitation.lastpage | 503 | |
local.identifier.doi | 10.1093/bioinformatics/btl601 | |
dc.date.updated | 2015-12-07T10:57:09Z | |
local.identifier.scopusID | 2-s2.0-33847292770 | |
Collections | ANU Research Publications |
Download
File | Description | Size | Format | Image |
---|---|---|---|---|
01_Frickey_Mclip:_Motif_detection_based_2007.pdf | 146.25 kB | Adobe PDF | Request a copy |
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.
Updated: 17 November 2022/ Responsible Officer: University Librarian/ Page Contact: Library Systems & Web Coordinator