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Towards Personalized Thrombosis Studies: <i>in situ</i> Mold-free Lithography of Physiological Stenosis in Circular Capillaries

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dc.contributor.authorLim, Yean J.en
dc.contributor.authorLi, Yongxiaoen
dc.contributor.authorGardiner, Elizabeth E.en
dc.contributor.authorLee, Woei M.en
dc.coverage.spatialSan Diegoen
dc.date.accessioned2025-06-24T01:35:54Z
dc.date.available2025-06-24T01:35:54Z
dc.date.issued2021en
dc.description.abstractStenotic blood vessels are like cylindrical tubes with undulating surfaces that generate highly unpredictable 3D micro-rheology. Using new adaptive optics and polygon scanning mirrors, we demonstrate precise and rapid in situ fabrication of customized stenosis in cylindrical glass capillaries. We showed that these personalized stenosis create highly non-uniform surface shear that impacts on localized thrombus growth and stability.en
dc.description.sponsorshipThis project was funded by the Australian Research Council (CE140100011, DE160100843, DP190100039).en
dc.description.statusPeer-revieweden
dc.identifier.isbn9781713855736en
dc.identifier.isbn9781733419031en
dc.identifier.otherORCID:/0000-0002-3912-6095/work/167893727en
dc.identifier.otherORCID:/0000-0001-9453-9688/work/167894532en
dc.identifier.scopus85136964932en
dc.identifier.urihttp://www.scopus.com/inward/record.url?scp=85136964932&partnerID=8YFLogxKen
dc.identifier.urihttps://www.proceedings.com/64786.htmlen
dc.identifier.urihttps://hdl.handle.net/1885/733764590
dc.language.isoenen
dc.publisherChemical and Biological Microsystems Societyen
dc.relation.ispartofMicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciencesen
dc.relation.ispartofseries25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021en
dc.rightsPublisher Copyright: © 2021 MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. All rights reserved.en
dc.subject2-photonen
dc.subjectCapillaryen
dc.subjectMicroscopyen
dc.subjectPhotolithographyen
dc.subjectPlateletsen
dc.subjectThrombusen
dc.titleTowards Personalized Thrombosis Studies: <i>in situ</i> Mold-free Lithography of Physiological Stenosis in Circular Capillariesen
dc.typeConference paperen
dspace.entity.typePublicationen
local.bibliographicCitation.lastpage1292en
local.bibliographicCitation.startpage1291en
local.contributor.affiliationLim, Yean J.; John Curtin School of Medical Research, ANU College of Science and Medicine, The Australian National Universityen
local.contributor.affiliationLi, Yongxiao; School of Engineering, ANU College of Systems and Society, The Australian National Universityen
local.contributor.affiliationGardiner, Elizabeth E.; John Curtin School of Medical Research, ANU College of Science and Medicine, The Australian National Universityen
local.contributor.affiliationLee, Woei M.; John Curtin School of Medical Research, ANU College of Science and Medicine, The Australian National Universityen
local.identifier.ariespublicationa383154xPUB39315en
local.identifier.pure653e0e0e-dd1f-4195-b297-72d3624fdcb8en
local.identifier.urlhttps://www.proceedings.com/64786.htmlen
local.identifier.urlhttps://www.scopus.com/pages/publications/85136964932en
local.type.statusPublisheden

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