Stereocontrolled aldol additions to α-methylene-β-alkoxy aldehydes: Application to the synthesis of a C<sub>13</sub>C<sub>25</sub> segment of bafilomycin A<sub>1</sub>

Simple item page
dc.contributor.authorPaterson, Ianen
dc.contributor.authorBower, Shelleyen
dc.contributor.authorMcLeod, Malcolm D.en
dc.date.accessioned2026-01-07T10:40:49Z
dc.date.available2026-01-07T10:40:49Z
dc.date.issued1995-01-02en
dc.description.abstractA boron-mediated, syn-aldol coupling between ethyl ketone 8 and aldehyde 9, followed by directed hydrogenation at C16 and acetonide hydrolysis, gives the C13C25 segment 6 of bafilomycin A1.en
dc.description.sponsorshipAcknowledgement: We thank the EPSRC (GR/J63019), EC (HCM Network CHRXCT930141), Pfizer Central Research, Cambridge Commonwealth Trust and Selwyn College for their support.en
dc.description.statusPeer-revieweden
dc.format.extent4en
dc.identifier.issn0040-4039en
dc.identifier.scopus0028891048en
dc.identifier.urihttps://hdl.handle.net/1885/733803918
dc.language.isoenen
dc.sourceTetrahedron Lettersen
dc.titleStereocontrolled aldol additions to α-methylene-β-alkoxy aldehydes: Application to the synthesis of a C<sub>13</sub>C<sub>25</sub> segment of bafilomycin A<sub>1</sub>en
dc.typeJournal articleen
dspace.entity.typePublicationen
local.bibliographicCitation.lastpage178en
local.bibliographicCitation.startpage175en
local.contributor.affiliationPaterson, Ian; University of Cambridgeen
local.contributor.affiliationBower, Shelley; University of Cambridgeen
local.contributor.affiliationMcLeod, Malcolm D.; University of Cambridgeen
local.identifier.citationvolume36en
local.identifier.doi10.1016/0040-4039(94)02205-Pen
local.identifier.pure5b00ea96-88fa-4a1d-8c57-55fb1c89c3fben
local.identifier.urlhttps://www.scopus.com/pages/publications/0028891048en
local.type.statusPublisheden

Downloads

Collections

ANU Research Publications

DSpace software copyright © 2002-2026 LYRASIS