Evaluating the quality of evidence for diagnosing ischemic heart disease from verbal autopsy in Indonesia

Abstract

BACKGROUND Mortality and cause of death data are fundamental to health policy development. Civil Registration and Vital Statistics systems are the ideal data source, but the system is still under development in Indonesia. A national Sample Registration System (SRS) has provided nationally representative mortality data from 128 sub-districts since 2014. Verbal autopsy (VA) is used in the SRS to obtain causes of death. The quality of VA data must be evaluated as part of the SRS data quality assessment.

AIM To assess the strength of evidence used in the assignment of Ischaemic Heart Disease (IHD) as causes of death from VA.

METHODS The sample frame for this study is the 4,070 deaths that had IHD assigned as the underlying cause in the SRS 2016 database. From these, 400 cases were randomly selected. A data extraction form and data entry template were designed to collect relevant data about IHD from VA questionnaires. A standardised categorisation was designed to assess the strength of evidence used to infer IHD as a cause of death. A pilot test of 50 cases was carried out. IBM SPSS software was used in this study.

RESULTS Strong evidence of IHD as a cause of death was assigned based on surgery for coronary heart disease, chest pain and two out of: sudden death, history of heart disease, medical diagnosis of heart disease, or terminal shortness of breath. More than half (53%) of the questionnaires contained strong evidence. For deaths outside health facilities, VA questionnaires for male deaths contained acceptable evidence in significantly higher proportions as compared to those for female deaths. (P < 0.001). Nearly half of all IHD deaths were concentrated in the 50-69 year age group (48.40%), and a further 36.10% were aged 70 years or more. Nearly two-thirds of the deceased were male (58.40%). Smoking behaviour was found in 44.11% of IHD deaths, but this figure was 73.82% among males.

CONCLUSION More than half of the VA questionnaires from the study sample were found to contain strong evidence to infer IHD as the cause of death. Results from medical records such as electrocardiograms, coronary angiographies, and load tests could have improved the strength of evidence and contributed to IHD cause of death diagnosis.

Key Words: Verbal autopsy, Data quality evaluation, Mortality, Cause of death

Core tip: In many countries in Southeast Asia, systems for recording mortality and causes of death are under development. In such settings, due to large proportions of deaths happening outside of health facilities, verbal autopsy interviews with families of the deceased are often used to ascertain the cause of death. However, there is a need to evaluate the quality of cause of death estimation from the verbal autopsy. This study specifically addresses the assignment of ischemic heart disease as a cause of death, concluding that a significant proportion of deaths were assigned this cause using strong evidence. Show more