Cultural advice

The Australian National University acknowledges, celebrates and pays our respects to the Ngunnawal and Ngambri people of the Canberra region and to all First Nations Australians on whose traditional lands we meet and work, and whose cultures are among the oldest continuing cultures in human history.

Aboriginal and Torres Strait Islander peoples are advised that ANU Library collections may include images, names, voices, and other representations of deceased persons.

Material in the collection may contain terms, language or views that reflect the period in which the item was created and may be considered inappropriate today.

Transcriptional Repressor Blimp-1 Promotes CD8 + T Cell Terminal Differentiation and Represses the Acquisition of Central Memory T Cell Properties

Thumbnail Image

Date

2009

Authors

Rutishauser, Rachel
Martins, Gislaine
Kalachikov, Sergey
Chandele, Anmol
Parish, Ian
Meffre, Eric
Jacob, Joshy
Calame, Kathryn
Kaech, Susan

Journal Title

Journal ISSN

Volume Title

Publisher

Cell Press

Abstract

During acute infections, a small population of effector CD8+ T cells evades terminal differentiation and survives as long-lived memory T cells. We demonstrate that the transcriptional repressor Blimp-1 enhanced the formation of terminally differentiated

Description

Keywords

Keywords: B lymphocyte induced maturation protein 1; interleukin 2; L selectin; repressor protein; animal cell; animal experiment; animal tissue; article; CD8+ T lymphocyte; cell survival; controlled study; lymphocyte differentiation; lymphocyte proliferation; Lymp CELLIMUNO; MOLIMMUNO

Citation

URI

http://hdl.handle.net/1885/37486

Collections

ANU Research Publications

Source

Immunity

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

10.1016/j.immuni.2009.05.014

Restricted until

2037-12-31

Downloads

File
Description
01_Rutishauser_Transcriptional_Repressor_2009.pdf (535.74 KB)

DSpace software copyright © 2002-2026 LYRASIS