Cultural advice

The Australian National University acknowledges, celebrates and pays our respects to the Ngunnawal and Ngambri people of the Canberra region and to all First Nations Australians on whose traditional lands we meet and work, and whose cultures are among the oldest continuing cultures in human history.

Aboriginal and Torres Strait Islander peoples are advised that ANU Library collections may include images, names, voices, and other representations of deceased persons.

Material in the collection may contain terms, language or views that reflect the period in which the item was created and may be considered inappropriate today.

Redefining mouse transgenesis with CRISPR/Cas9 genome editing technology

Thumbnail Image

Date

2018

Authors

Burgio, Gaetan

Journal Title

Journal ISSN

Volume Title

Publisher

BioMed Central

Abstract

The generation of genetically modified alleles in mice using conventional transgenesis technologies is a long and inefficient process. A new study shows that the in situ delivery of CRISPR/Cas9 reagents into pregnant mice results in a high efficiency of editing, and enables the rapid generation of both simple and complex alleles.

Description

Keywords

Citation

URI

http://hdl.handle.net/1885/251973

Collections

ANU Research Publications

Source

Genome Biology

Type

Journal article

Book Title

Entity type

Access Statement

Open Access

License Rights

Creative Commons Attribution 4.0 International License

DOI

10.1186/s13059-018-1409-1

Restricted until

Downloads

File
Description
01_Burgio_Redefining_mouse_transgenesis_2018.pdf (360.91 KB)

DSpace software copyright © 2002-2026 LYRASIS

abcd