Cultural advice

The Australian National University acknowledges, celebrates and pays our respects to the Ngunnawal and Ngambri people of the Canberra region and to all First Nations Australians on whose traditional lands we meet and work, and whose cultures are among the oldest continuing cultures in human history.

Aboriginal and Torres Strait Islander peoples are advised that ANU Library collections may include images, names, voices, and other representations of deceased persons.

Material in the collection may contain terms, language or views that reflect the period in which the item was created and may be considered inappropriate today.

Genotoxicity and transmission electron microscopy studies of molybdocene dichloride

Date

Authors

Campbell, Kate S

Foster, Amalanie J

Dillon, Carolyn

Harding, Margaret

Publisher

Elsevier

Abstract

The cytotoxic effects of molybdocene dichloride (Cp2MoCl2) were investigated in V79 Chinese hamster lung cells using the micronucleus assay. Cp2MoCl2 produced significant genotoxic damage whereby 0.2 micronuclei/1000 binucleated cells were induced per μM

Keywords

Keywords: antineoplastic agent; metal complex; molybdocene dichloride; unclassified drug; animal cell; antineoplastic activity; article; cell damage; cell ultrastructure; CHO cell; chromatin condensation; controlled study; cytotoxicity; drug structure; genotoxicity Antitumor metallocene; Genotoxicity; Micronucleus assay; Molybdocene dichloride; TEM

URI

http://hdl.handle.net/1885/73564

Collections

ANU Research Publications

Source

Journal of Inorganic Biochemistry

Type

Journal article

DOI

10.1016/j.jinorgbio.2006.01.034

Restricted until

2037-12-31

Downloads

File

Description

01_Campbell_Genotoxicity_and_transmission_2006.pdf (232.94 KB)