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Predictors of alcohol and substance use among people with post-traumatic stress disorder (PTSD): findings from the NESARC-III study

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dc.contributor.authorDell�Aquila, Adriana
dc.contributor.authorBerle, David
dc.date.accessioned2024-07-02T00:28:07Z
dc.date.available2024-07-02T00:28:07Z
dc.date.issued2023
dc.date.updated2024-05-19T08:17:21Z
dc.description.abstractPurpose The self-medication hypothesis suggests people may develop Alcohol Use Disorder (AUD) or Non-Alcohol Substance Use Disorder (NA-SUD) following PTSD as a maladaptive way of coping with PTSD symptoms. Given that an accumulation of trauma experiences and interpersonal trauma increase the likelihood and severity of PTSD, we sought to determine whether the number and type of traumas additionally predict AUD and NA-SUD following PTSD. Methods We analysed data from 36,309 adult participants in the National Epidemiologic Survey on Alcohol and Related Conditions-III (NESARC-III) study (M = 45.63 years, SD = 17.53, 56.3% female) who were administered semi-structured diagnostic interviews of trauma exposure and PTSD, AUD and NA-SUD symptoms. Results Individuals with PTSD were more likely to have an AUD or NA-SUD than those without PTSD. Endorsement of a greater number of traumas was associated with greater odds of having PTSD, AUD, or NA-SUD. Experience of interpersonal trauma was related to greater odds of having PTSD and subsequent AUD or NA-SUD than not experiencing interpersonal trauma. Multiple experiences of interpersonal trauma compared to one interpersonal trauma exposure also increased the odds of having PTSD followed by AUD or NA-SUD. Conclusions Interpersonal trauma and multiple experiences of interpersonal trauma may result in individuals turning to alcohol and substances as a way to alleviate intolerable PTSD symptomology, aligning with the self-medication hypothesis. Our findings highlight the importance of ensuring services and support for interpersonal trauma survivors and for those who have experienced multiple traumas given their increased for unfavourable outcomes.
dc.description.sponsorshipOpen Access funding enabled and organized by CAUL and its Member Institutions.
dc.format.mimetypeapplication/pdfen_AU
dc.identifier.issn09337954
dc.identifier.urihttps://hdl.handle.net/1885/733713622
dc.language.isoen_AUen_AU
dc.provenanceThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
dc.publisherDr Dietrich Steinkopff Verlag
dc.rights© 2023 The authors
dc.rights.licenseCreative Commons Attribution licence
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.sourceSocial Psychiatry and Psychiatric Epidemiology
dc.subjectPost-traumatic stress disorder (PTSD) ·
dc.subjectAlcohol use disorder (AUD)
dc.subjectSubstance use disorder (SUD)
dc.subjectTrauma exposure
dc.subjectInterpersonal trauma
dc.subjectSelf-medication hypothesis
dc.titlePredictors of alcohol and substance use among people with post-traumatic stress disorder (PTSD): findings from the NESARC-III study
dc.typeJournal article
dcterms.accessRightsOpen Access
local.bibliographicCitation.lastpage1522
local.bibliographicCitation.startpage1509
local.contributor.affiliationDell'Aquila, Adriana, University of Technology Sydney
local.contributor.affiliationBerle, David, College of Health and Medicine, ANU
local.contributor.authoremailu3089467@anu.edu.au
local.contributor.authoruidBerle, David, u3089467
local.description.notesImported from ARIES
local.identifier.absfor420200 - Epidemiology
local.identifier.absfor520300 - Clinical and health psychology
local.identifier.ariespublicationa383154xPUB43549
local.identifier.citationvolume58
local.identifier.doi10.1007/s00127-023-02472-6
local.identifier.scopusID2-s2.0-85158099125
local.identifier.uidSubmittedBya383154
local.publisher.urlhttps://link.springer.com/
local.type.statusPublished Version

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