A total synthesis of the marine alkaloid ningalin B from ( S )-proline

Hasse, Katrin; Willis, Anthony; Banwell, Martin

Cultural advice

The Australian National University acknowledges, celebrates and pays our respects to the Ngunnawal and Ngambri people of the Canberra region and to all First Nations Australians on whose traditional lands we meet and work, and whose cultures are among the oldest continuing cultures in human history.

Aboriginal and Torres Strait Islander peoples are advised that ANU Library collections may include images, names, voices, and other representations of deceased persons.

Material in the collection may contain terms, language or views that reflect the period in which the item was created and may be considered inappropriate today.

A total synthesis of the marine alkaloid ningalin B from ( S )-proline

Date

2009

Authors

Hasse, Katrin

Willis, Anthony

Banwell, Martin

Publisher

CSIRO Publishing

Abstract

The title alkaloid 1 has been synthesized from (S)-proline (2) using a sequence of reactions involving oxidative bromination (of 2), N-alkylation, SuzukiMiyaura cross-coupling, and bromination steps.