Improved robust performance in a system for automatic administration of a vasoactive drug

Date

2012

Authors

Malagutti, Nicolò
Dehghani, Arvin
Kennedy, Rodney

Journal Title

Journal ISSN

Volume Title

Publisher

Springer

Abstract

The problem of automatic administration of vasoactive drugs to regulate mean arterial pressure in surgical and postsurgical patients can be considered as a setpoint tracking problem involving a system which is characterised by significant modelling uncertainty in the form of uncertain parameters, unmodelled dynamics and disturbances. Yet, specific levels of performance are required and patient safety must be guaranteed. As part of the development process of a novel Multiple-Model Adaptive Control (MMAC) architecture for this application, we have adopted a mixed-μ synthesis approach to controller design. Simulation results show that the new controllers are capable of improved disturbance rejection and robustness even in the face of large system delays and parametric uncertainty.

Description

Keywords

Keywords: Adaptive Control; Anaesthesia; Controller designs; Development process; Intensive care; Large system; Mean arterial pressure; Multiple-model adaptive controls; Parametric uncertainties; Patient safety; Robust performance; Set-point tracking; Uncertain par Adaptive control; Anaesthesia; Automatic control; Blood pressure; Drug delivery; Intensive care; Robust control

Citation

Source

BIOSIGNALS 2012 - Proceedings of the International Conference on Bio-Inspired Systems and Signal Processing

Type

Conference paper

Book Title

Entity type

Access Statement

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DOI

Restricted until

2037-12-31