Inhibitory role of peroxisome proliferator-activated receptor gamma in hepatocarcinogenesis in mice and in vitro

Date

2010

Authors

Yu, Jun
Shen, Bo
Chu, Eagle S. H.
Teoh, Narcissus
Cheung, Kin F
Wu, Chung W
Wang, Shiyan
Lam, Cleo N Y
Feng, Hai
Zhao, Junhong

Journal Title

Journal ISSN

Volume Title

Publisher

W B Saunders Co

Abstract

Although peroxisome proliferator-activated receptor gamma (PPARγ) agonist have been shown to inhibit hepatocellular carcinoma (HCC) development, the role of PPARγ in hepatocarcinogenesis remains unclear. We investigated the therapeutic efficacy of PPAR�

Description

Keywords

Keywords: adenovirus vector; caspase 3; caspase 7; caspase 9; diethylnitrosamine; Fas antigen; growth differentiation factor 15; peroxisome proliferator activated receptor gamma; poly(adenosine diphosphate ribose); rosiglitazone; tumor necrosis factor alpha; allele

Citation

Source

Hepatology

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

Restricted until

2037-12-31