Dynamic and Responsive Growth Factor Delivery from Electrospun and Hydrogel Tissue Engineering Materials

Date

2017-11-30

Authors

Bruggeman, Kiara
Williams, Richard James
Nisbet, David

Journal Title

Journal ISSN

Volume Title

Publisher

Wiley-VCH Verlag GmbH & Co. KGaA.

Abstract

Tissue engineering scaffolds are designed to mimic physical, chemical, and biological features of the extracellular matrix, thereby providing a constant support that is crucial to improved regenerative medicine outcomes. Beyond mechanical and structural support, the next generation of these materials must also consider the more dynamic presentation and delivery of drugs or growth factors to guide new and regenerating tissue development. These two aspects are explored expansively separately, but they must interact synergistically to achieve optimal regeneration. This review explores common tissue engineering materials types, electrospun polymers and hydrogels, and strategies used for incorporating drug delivery systems into these scaffolds.

Description

Keywords

drug delivery, electrospinning, hydrogel, regenerative medicine, tissue engineering

Citation

Source

Advanced Healthcare Materials

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

10.1002/adhm.201700836

Restricted until

2099-12-31