Childhood adversity and midlife suicidal ideation
dc.contributor.author | Stansfeld, S A | |
dc.contributor.author | Clark, C | |
dc.contributor.author | Smuk, M | |
dc.contributor.author | Power, C | |
dc.contributor.author | Davidson, T | |
dc.contributor.author | Rodgers, Bryan | |
dc.date.accessioned | 2017-03-28T05:46:15Z | |
dc.date.available | 2017-03-28T05:46:15Z | |
dc.date.issued | 2017-01 | |
dc.description.abstract | BACKGROUND Childhood adversity predicts adolescent suicidal ideation but there are few studies examining whether the risk of childhood adversity extends to suicidal ideation in midlife. We hypothesized that childhood adversity predicts midlife suicidal ideation and this is partially mediated by adolescent internalizing disorders, externalizing disorders and adult exposure to life events and interpersonal difficulties. METHOD At 45 years, 9377 women and men from the UK 1958 British Birth Cohort Study participated in a clinical survey. Childhood adversity was prospectively assessed at the ages of 7, 11 and 16 years. Suicidal ideation at midlife was assessed by the depressive ideas subscale of the Revised Clinical Interview Schedule. Internalizing and externalizing disorders were measured by the Rutter scales at 16 years. Life events, periods of unemployment, partnership separations and alcohol dependence were measured through adulthood. RESULTS Illness in the household, paternal absence, institutional care, parental divorce and retrospective reports of parental physical and sexual abuse predicted suicidal ideation at 45 years. Three or more childhood adversities were associated with suicidal ideation at 45 years [odds ratio (OR) 4.31, 95% confidence interval (CI) 2.67-6.94]. Psychological distress at 16 years partially mediated the associations of physical abuse (OR 3.41, 95% CI 2.29-5.75), sexual abuse (OR 4.99, 95% CI 2.90-11.16) with suicidal ideation. Adult life events partially mediated the association of parental divorce (OR 6.34, 95% CI -7.16 to 36.75) and physical (OR 9.59, 95% CI 4.97-27.88) and sexual abuse (OR 6.59, 95% CI 2.40-38.36) with suicidal ideation at 45 years. CONCLUSIONS Adversity in childhood predicts suicidal ideation in midlife, partially mediated by adolescent internalizing and externalizing disorders, adult life events and interpersonal difficulties. Understanding the pathways from adversity to suicidal ideation can inform suicide prevention and the targeting of preventive interventions. | en_AU |
dc.description.sponsorship | The biomedical examination and related statistical analyses were funded by the Medical Research Council (grant no. G0000934), awarded under the Health of the Public initiative. B.R. was supported by Research Fellowship no. 471429 from the National Health and Medical Research Council of Australia. Research at the UCL Institute of Child Health and Great Ormond Street Hospital for Children is supported by the Department of Health’s National Institute of Health Research (NIHR) Biomedical Research Centre. | en_AU |
dc.format.mimetype | application/pdf | en_AU |
dc.identifier.issn | 0033-2917 | en_AU |
dc.identifier.uri | http://hdl.handle.net/1885/114093 | |
dc.relation | http://purl.org/au-research/grants/nhmrc/471429 | en_AU |
dc.rights | © Cambridge University Press 2016. This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited. | en_AU |
dc.source | Psychological medicine | en_AU |
dc.subject | adversity | en_AU |
dc.subject | childhood psychological disorders | en_AU |
dc.subject | cohort studies | en_AU |
dc.subject | suicide | en_AU |
dc.title | Childhood adversity and midlife suicidal ideation | en_AU |
dc.type | Journal article | en_AU |
dcterms.accessRights | Open Access | en_AU |
local.bibliographicCitation.issue | 2 | en_AU |
local.bibliographicCitation.lastpage | 340 | en_AU |
local.bibliographicCitation.startpage | 327-340 | en_AU |
local.contributor.affiliation | Rodgers, B., School of Demography, The Australian National University | en_AU |
local.contributor.authoremail | Bryan.Rodgers@anu.edu.au | en_AU |
local.contributor.authoruid | u9210598 | en_AU |
local.identifier.citationvolume | 47 | en_AU |
local.identifier.doi | 10.1017/S0033291716002336 | en_AU |
local.identifier.essn | 1469-8978 | en_AU |
local.identifier.uidSubmittedBy | u1005913 | en_AU |
local.type.status | Published Version | en_AU |
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